TRLUP – Spheralis Biolabs : Mise à l’échelle de composés PC

Le projet vise à optimiser la production d’un nouvel antibiotique conçu pour traiter les infections du pis chez les vaches, causées par Staphylococcus aureus. Ces infections coûtent très cher à l’industrie laitière et les traitements actuels sont souvent inefficaces ou contrôlés en médecine vétérinaire. Le stagiaire travaillera avec le centre de recherche appliquée Kemitek pour […]

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TRLUP – NeuroSpritz

Electroencephalogram (EEG) setup and application are time consuming (current solutions involve ~50.3 minutes of setup/patient or participant) and requires expert application (making it inaccessible to many). The extensive time to setup EEGs limits the number of research participants and patients that a researcher or clinician can see in one day. This problem directly impacts research […]

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Investigating the organohalide dehalogenation respiratory chain of Dehalococcoides mccartyi CBDB1

Organohalide-respiring bacteria (OHRB) are important agents of bioremediation, helping to clean up groundwater contaminated with toxic compounds such as chloroform, perchloroethene (PCE), and chlorobenzene. This metabolic pathway relies on enzymes known as reductive dehalogenase homologs (RdhAs). The mechanisms by which RdhAs reduce organohalides remains elusive, particularly in the case of the Chloroflexi OHRB Dehalococcoides and […]

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Prevention of hepatitis C virus (HCV) re-infection afterliver transplantation

Over 170 million persons worldwide are chronically infected by hepatitis C virus (HCV), leading to endstage liver disease and cancer. HCV is the single most common indication for liver transplantation in Canada and the rest of the Western world. After transplant, HCV re-infection is universal and is the chief cause of graft loss. Treatment of […]

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TRLUP– Secreted protein acidic and rich in cysteine (SPARC): Towards a pharmacologic exercise substitute

Secreted protein acidic and rich in cysteine (SPARC) is a protein that is more produced by athletes (muscles) compared to sedentary individuals. We have previously shown that this protein is responsible for some exercise-induced effects, its injections also produce exercise-like effects, and its decrease/absence speeds up ageing. Therefore, SPARC could be an exercise substitute – […]

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Reducing socioeconomic inequalities in adult cardiovascular disease risk by addressing unhealthy movement behaviours during adolescence: A population-based intervention modelling study

Youth from lower socioeconomic backgrounds are more likely to develop heart disease as adults, partly because they face more challenges meeting physical activity, screen time, and sleep recommendations. This study will examine how improving these movement behaviours during adolescence could reduce future health inequalities. Using data from a long-term United States study that has followed […]

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Development and characterization of SSE-compatible inks for point-of-care 3D printing of pediatric drugs

La stagiaire participera à la conception d’encres pharmaceutiques pour l’impression 3D de comprimés mâchables destinés à l’usage pédiatrique. Cette nouvelle technologie permet de fabriquer de façon rapide et sécuritaire des imprimés gélifiés contenant une dose personnalisée d’un ou plusieurs médicaments. La stagiaire mettra au point de nouvelles formulations d’encres imprimables et en assurera la caractérisation, […]

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Virtual reality as a strategy for intra-operatory anxiolysis and pharmacological sparing in patients undergoing breast surgeries: the V-RAPS randomized controlled trial

This project will explore the use of virtual reality (VR) to reduce the need for sedative medication during breast surgeries performed under regional anesthesia. Currently, patients undergoing these procedures often receive intravenous sedative medication to ease anxiety, which can lead to complications like breathing problems or longer recovery times. VR immersion, which has already been […]

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