The treatment of Hospital acquired infections from pathogenic bacteria continues to be a serious and significant burden on health care resources both nationally and globally. Currently, about 1 in 10 persons will acquire an HAI as result of a medical procedure which can result in an additional hospital stay, treatment and in some severe cases, […]

Optimiser la production porcine au Canada est un défi majeur puisque ses acteurs sont en concurrence avec ceux des pays où les coûts de production sont moindres. Il est impératif pour une telle optimisation de repenser ses programmes de sélection, de considérer la nécessité de diversifier son offre et d’améliorer le bien-être animal. En combinant […]

Un des facteurs les plus importants du succès de la fécondation in vitro est la qualité de culture de l’embryon. Un nouveau milieu de culture a été créé en utilisant les propres cellules endométriales de la patiente. Le but est d’évaluer l’efficacité d’un transfert d’embryon au stade de blastocyste après la mise en co-culture avec […]

Chocolates have a rich source of dietary phenolic compounds and antioxidants. During chocolate manufacture, the antioxidant capacity and procyanidin content in cocoa can be affected by a variety of processing conditions. Therefore, a rapid and less expensive method to determine chocolate antioxidants is highly demanded in confectionery industry. As a nondestructive tool, Fourier transform infrared […]

Health economic evaluation provides information about the value for money of new healthcare technologies, and is increasingly used to guide the allocation of scarce resources based on maximizing health gain. The molecular diagnostics company, PDI, has developed a technology to improve the identification of patients at high risk for oral cancers for early intervention, and […]

Probiotics are suggested to greatly reduce the risk of mortality and risk of infection in the gut of preterm infants. However, probiotics are rarely given to babies in hospitals in North America. The aim of this study is to assess the effectiveness of probiotics supplementation in improving intestinal heath and preventing gut complications in premature […]

There is an urgent need for the development of new tools that can provide a relatively highthroughput, objective assessment of brain function in individuals with neurodevelopmental, neurodegenerative or psychiatric disorders. The overarching objective of this research proposal is to use eye movement tasks to identify biomarkers that can be used in the assessment of brain […]

Osteoarthritis (OA) is a growing burden in an aging society. There are few proven treatments and hence disability contributes to poor quality of life and direct/indirect costs to society. Hyaluronic acids have been show to improve OA symptoms but usually the onset is delayed by weeks. Corticosteroid therapy in contrast has a quick onset of […]

Each year, about 4 millions of newborn babies die from infectious causes worldwide. Birth represents a major immunological transition from a safer environment to a microbiologically hostile outside world. T cells are key players of the immune system and newborn babies do not display a strong immunological response as most of their T cells are […]

Highly targeted therapies can be devised to treat a variety of cancers, specifically acting on the mutated genes causing tumor growth. One challenge with such techniques is delivering the therapy to the interior of the cancer cell, when enzymes in the blood can actively break down the therapeutic molecules or when delivery to healthy cells […]

Many genetic diseases caused by small genetic mutations do not result in complete loss of protein fnction, but rather are due to the degradation of mutant protein by a “quality control” mechanism (endoplasmic reticulum-associated degradation-ERAD) soon after it is made. Prominent amongst such ERAD-dependent diseases is Cystic Fibrosis(CF), a chronic, progressive, life-threatening genetic disease that […]

Some social mammals present a group dynamic related to spatially and temporally variable environments described as fission-fusion dynamics. This dynamics is defined as the temporal division of a group into sub-groups varying in size and composition, and is thought to occur through social regulation to improve foraging efficiency. Nevertheless, the influential factors in that dynamics […]