Host-pathogen interaction between a three-dimensional tissue model with a binary cell system and dual species biofilm Under Normoglycemic and Diabetic Conditions

Apical periodontitis is a disease caused by the persistence of microorganisms and their virulence factors in the root canal system. This infection leads to inflammation of the soft tissues and changes in the periapical bone structure. Bacteria such as Fusobacterium nucleatum and Parvimonas micra form biofilms that are resistant to conventional cleaning, making treatment more […]

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L2M – Neuro-integrated carbene coatings

Brain-Computer Interfaces (BCIs) are a revolutionary technology with the potential to significantly improve the lives of individuals with neurological disorders, but their long-term use is severely limited because the implants often fail within a short period. This project, a collaboration with Queen’s University, aims to solve this critical problem by developing and commercializing “Neuro-Integrated Carbene […]

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Mixed Methods in Indigenous Health Research: Colombia, Canada & the Caribbean

In 2020, there were 19.3 million new cancer cases and 9.9 million related deaths, with 70% occurring in low- and middle-income countries. In Latin America, cancer remains a leading cause of mortality, with cases projected to rise from 4 million in 2020 to 6 million by 2040. Indigenous populations are among the most affected; in […]

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L2M – Developing Machine Learning Models to Accelerate our In-Vivo Creatinine and Potassium Biosensor Development

Many people with heart failure are not prescribed the full set of guideline-directed medical therapies (GDMT), which can shorten their lifespan and reduce quality of life. One major reason is the difficulty and inconvenience of regularly checking potassium and creatinine levels, which are needed to safely adjust these medications. To address this, we are developing […]

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L2M_BSI Proposal_L2M Health Validate Helixir

Our academic lab has developed technology that could have potential benefits in the Canadian healthcare system. This technology is highly specialized that combines MRI and interventional cardiac treatment. The intern will determine if our technology can satisfy the needs dictated by various stakeholders in the industry, such that a startup is warranted. This objective will […]

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L2M Validate – Pi16 Therapeutics

The mission of PI16 Therapeutics is to improve skin health for the ~4 million Canadian’s suffering from long-term skin diseases, including clinically dry skin, chronic wounds, and severe burns. PI16 Therapeutics aims to produce skin solutions for these individuals by genetically engineering naturally occurring stem-cell like fibroblasts that express the gene Peptidase Inhibitor 16 (Pi16) […]

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L2M – U-Pro Soccer

U-Pro Soccer is a Canadian sportstech company developing a mobile-first training platform that uses AI and computer vision to help youth athletes practice soccer drills at home using only a smartphone and a training mat. Many young players lack access to structured training, especially outside of team environments, and U-Pro aims to fill this gap […]

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Dans quelle mesure le modèle opérationnel actuel du département de pharmacovigilance au Canada, qui adhère à un cadre mondial, répond-il efficacement aux besoins et aux défis spécifiques de l’affilié canadien?

Le projet de recherche examinera dans quelle mesure le système actuel de pharmacovigilance au Canada s’aligne sur les normes mondiales tout en répondant aux défis réglementaires locaux. La pharmacovigilance assure la sécurité des médicaments en surveillant et en gérant les risques potentiels. Bien que le Canada suive les lignes directrices internationales, il dispose également de […]

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Vers une industrie pharmaceutique sans PFAS : Évaluation des risques et stratégies d’atténuation pour une production plus sûre

Les substances per- et polyfluoroalkylées (PFAS) sont des produits chimiques utilisés pour leurs propriétés résistantes à l’eau et à l’huile, mais elles sont aussi très persistantes dans l’environnement et peuvent nuire à la santé humaine. Ce projet vise à étudier la présence des PFAS dans les produits pharmaceutiques, un domaine encore peu exploré. En collaboration […]

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Évaluation des modalités de traitements des chondrosarcomes extra-squelettiques, rôle de la radiothérapie néo adjuvante

Les chondrosarcomes extra-squelettiques sont des tumeurs rares dont le traitement repose principalement sur la chirurgie. Toutefois, l’ajout d’une radiothérapie avant l’opération (radiothérapie néo-adjuvante) pourrait aider à réduire la taille de la tumeur et faciliter son retrait. Ce projet de recherche vise à mieux comprendre les bénéfices et les risques de cette approche en comparant des […]

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L2M – Bacterial Amplicon Tick Test (BATT)

Tick-borne diseases, including Lyme disease and Anaplasmosis, are an increasing public health concern in Canada, with rising case numbers driven by climate change and expanding tick populations. Current testing methods are limited as they typically detect only one pathogen at a time and often miss early-stage infections. As a result, many Canadians can go undiagnosed […]

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L2M DialySnake: A novel, minimally invasive tool to remove intraluminal fibrin plugs and restore peritoneal dialysis catheter patency

This project will focus on helping to bring the DialySnake, which is a novel medical device, closer to market. The DialySnake is a low-cost, minimally invasive tool designed to unclog blocked peritoneal dialysis (PD) catheters at patients’ bedsides in an average of 5 minutes. Currently, when peritoneal dialysis catheters become blocked, hospitals often rely on […]

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