Rapid next generation infectious disease diagnostics for tuberculosis and leptospirosis

Infectious diseases remain one of the largest killers of the human population and disproportionately so in developing countries. Assays for the rapid and comprehensive identification of causative strains of the infectious disease agents in tuberculosis and leptospirosis is currently lacking. These infections represent over 20 million cases annually. Existing diagnostic protocols involve lengthy and resource-intensive […]

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High-Affinity Selective DNA Intercalators (HASDI): A novel approach to interfere with the transcriptional activity of disease-causing transcription factors

Cancer is a complex disease that involves multiple changes in normal cell biology, all of them leading to increased and abnormal cell replication. Depending on the tissue type, this uncontrolled tissue growth ultimately causes organ malfunction and a wide variety of signs and symptoms which, all together, indicate a pathological state which needs to be […]

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Endovation

This project focuses on extending Neuraura’s LoOoP neurostimulation platform to address the unmet needs of individuals with endometriosis—a chronic, debilitating condition affecting 1 in 10 individuals with a uterus. While TENS therapy is already used for symptom relief, Neuraura is exploring its potential to influence tissue behavior and possibly slow or reverse lesion growth. To […]

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Feasibility and Usability Testing of a Digital Reminiscence Platform

This project will test and improve Voiced Memories, a Canadian-made digital storytelling tool designed for older adults and caregivers. The platform allows people to pair personal photos with recorded voice stories, creating “digital memory galleries” that can be revisited, shared, and used to spark conversation. The research will take place in two settings: Memory Cafés […]

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Investigating food web rewiring under drought

Human activities are modifying the planet in many ways, via climate change, land use change, and environmental contamination. This is accelerating species extinction across the tree of life. Safeguarding biodiversity requires an accurate understanding of how nature is organized—species interact with each other in complex networks, such as when a predator consumes a prey, or […]

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Imaging Biomarkers for Nanotherapeutics

Poor drug accumulation at tumor sites negatively affects the efficacy of many anti-cancer therapeutics. Development of non-invasive strategies that can effectively monitor drug biodistribution is important, especially given the increasing number and complexity of nanotherapeutic agents in clinical development. The use of positron emission tomography in conjunction with a radiolabeled drug delivery system has the […]

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VR Gaze and Head Dynamics

Most of what we know about how people attend to the world comes from lab studies where participants sit still and look at flat images on a screen. But in everyday life, we move our heads and bodies freely to explore our surroundings. With new Virtual Reality (VR) technology that includes eye and head tracking, […]

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Imaging Biomarkers for Nanotherapeutics – Year two

Poor drug accumulation at tumor sites negatively affects the efficacy of many anti-cancer therapeutics. Development of non-invasive strategies that can effectively monitor drug biodistribution is important, especially given the increasing number and complexity of nanotherapeutic agents in clinical development. The use of positron emission tomography in conjunction with a radiolabeled drug delivery system has the […]

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Fundamental understanding of brewing phenomena and shelf-life extension of single-serve coffee

Brewing of premium coffee in single-serve capsule is challenging due to many design and machine constraints. Moreover, parameters that affect the brew quality are not fully understood. By collaborating with Mother Parkers Tea and Coffee Inc., this project will systematically evaluate the brewing parameters on the physical and sensorial properties of drip and espresso coffees. […]

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Fundamental understanding of brewing phenomena and shelf-life extension of single-serve coffee – Year two

Brewing of premium coffee in single-serve capsule is challenging due to many design and machine constraints. Moreover, parameters that affect the brew quality are not fully understood. By collaborating with Mother Parkers Tea and Coffee Inc., this project will systematically evaluate the brewing parameters on the physical and sensorial properties of drip and espresso coffees. […]

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