Canagliflozin to improve enzalutamide response and suppress resistance in hormone-sensitive and castrate resistant prostate cancer (PrCa).

In this study, researchers aim to investigate whether canagliflozin, an anti-diabetic agent, can enhance the effectiveness of enzalutamide in preclinical models of prostate cancer (PrCa). Prostate cancer often becomes resistant to current therapies, such as enzalutamide, due to various molecular pathways. Canagliflozin has shown promise in suppressing these pathways in prostate cancer cells and tumors, […]

Read More
Étude palynologique de deux régions de la Côte-Nord au Québec : effets des feux et du climat sur la végétation boréale

Les forêts boréales, couvrant 10 % de la surface terrestre, sont essentielles à notre planète. Elles stockent du carbone, régulent le climat, fournissent des ressources comme le bois ou le papier, et abritent une riche biodiversité. Cependant, elles sont menacées par les changements climatiques, qui entraînent des feux de forêt plus fréquents et intenses, modifiant […]

Read More
Étude du lien entre la taille des artères, les niveaux de sténose et la cognition – Étude de Tromsø

Le projet proposé vise à évaluer l’impact des sténoses, c’est-à-dire un rétrécissement de l’artère, sur la cognition, en particulier comment leur présence et leur localisation affectent divers domaines cognitifs, comme la mémoire et les habiletés motrices. L’étude se distingue par l’utilisation d’outils de caractérisation des artères développés à Sherbrooke, incluant un algorithme capable de détecter […]

Read More
Réalité virtuelle immersive : un outil innovant pour le bien-être des personnes atteintes de démence dans les établissements de soins de longue durée du Québec

Ce projet utilise la réalité virtuelle immersive pour améliorer le bien-être des personnes aînées vivant avec une démence en établissements de soins de longue durée (CHSLD et MDA/MDAA). La pleine conscience, une pratique consistant à se concentrer sur le moment présent pour réduire le stress et l’anxiété, est au cœur de cette initiative. Grâce à […]

Read More
Audio Hardware Calibration and Audiometry

This project is to focus on building an application that can be used to perform a audiology-grade calibration of consumer headphones (and microphones) on a mobile device (such as an iPhone or iPad). The intern will use mathematical techniques (such as spectral analysis) to help gather and analyze user information more efficiently in order to […]

Read More
Climate-conscious waste diversion for households in Fredericton, NB

Climate-Conscious Waste Diversion for Households in Fredericton This internship will assist the Fredericton Community Climate Hub initiate discussions with City residents on climate-conscious lifestyle choices by engaging them in practices to reduce or eliminate household wastes. The intern will research, analyse and synthesize the disparate programs for citizens to actively employ the 7Rs (rethink, refuse, […]

Read More
Correlation between trophoblast cell-surface antigen-2 (TROP-2) expression measured using conjugated Gold nanoparticles and ADC response in breast cancer cells.

According to a WHO report in 2022, one in five people are at risk of developing cancer, but only 39% of countries provide comprehensive health coverage. The most common cancers are lung, breast, and colorectal. Chemotherapy and radiotherapy, while common, present challenges due to their side effects and low specificity. New targeted therapies, such as […]

Read More
Behavioral Dysfunctions After Preterm Birth: The Role of Vasopressin

This project aims to explore the role of arginine vasopressin (AVP) in cognitive and anxiety-like behavior dysfunctions observed in preterm birth models. Using a neonatal hyperoxia rat model, which mimics bronchopulmonary dysplasia (BPD) and associated complications of preterm birth, the study will assess behavioral outcomes and AVP levels in different experimental conditions. The findings are […]

Read More
Etiology, prevention and rehabilitation of shoulder injuries in elite swimmers and waterpolo players: a longitudinal study

Chronic shoulder injuries are common in athletes competing in overhead sports such as waterpolo, swimming and synchronized swimming. These injuries are costly both financially and in terms of performance to the athletes and sport organizations. The purpose of this project is to create new sport-specific clinical and functional assessment protocols and to improve training strategies […]

Read More
Sex differences and body morphology on thermal discomfort thresholds during rest and exercise

Thermal comfort can be broadly defined as a scenario where an individual expresses satisfaction with their thermal environment. However, our thermal environment is rarely constant, and these changes in our thermal environment can negatively affect our thermal comfort. Additionally, a certain thermal environment can be comfortable for one person but uncomfortable for another, because our […]

Read More
Access to Spirometry in Nova Scotia

test it is difficult to get a correct diagnosis of lung disease, and most importantly to get started on the right treatments. In this study we will 1) describe the quality of breathing tests done in the community; and 2) compare review and interpretation of breathing tests by a doctor to an artificial intelligence algorithm […]

Read More