Mieux comprendre la prise de décision clinique pour la lombalgie en première ligne de soins : une approche par méthodes mixtes.

L’un des plus grands défis pour le système de soins de santé québécois est l’augmentation des coûts et du fardeau social associés aux maladies chroniques. Parmi celles-ci, les maux de dos sont responsables de la majeure partie des coûts engendrés par les conditions qui touchent le système musculosquelettique. Nombreux sont les patients qui consultent en […]

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Genetic Diversity of Southern African Cannabis

This research project has the overall objective of further studying the genetic diversity of South African cannabis landraces, with the goal of understind how they relate to other wile and landrace cannabis populations worldwide. This knowledge will help understanding the unique characteristics and adpatation of South African cannabis landraces, and reconstructing the human-mediated dispersal of […]

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Post-Arthroscopy Strength Recovery in Patients Treated for Femoroacetabular Impingement

This study aims to assess the improvement in muscle strength in patients with femoroacetabular impingement (FAI) after undergoing hip arthroscopy. FAI can cause severe hip pain and functional limitations, potentially leading to early osteoarthritis. While arthroscopic treatment often have good results, dissatisfaction rates can be as high as 30%. This research investigates the potential benefits […]

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Evaluation of heat stress in lifeguards

Due to climate change, exposure to increasingly warmer temperatures, especially during the summer months, is of concern. This is true for lifeguards who play a vital role in ensuring the safety and well-being of visitors to aquatic facilities as well as beachfronts open for public swimming. Due to routine exposure to hot and humid conditions, […]

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Evaluation of anti-invasive and anti-migratory effects of kaempferol and docetaxel co-treatment via modulation of drug metabolising enzymes in 2D and 3Dbreast cancer models.

Docetaxel is a key chemotherapeutic agent for treating locally advanced or metastatic breast cancer, but its effectiveness is often hindered by metabolic inactivation from drug-metabolizing enzymes, leading to multidrug resistance (MDR). This study aims to investigate the anti-metastatic effects of combining kaempferol, a flavonoid known for its anticancer properties, with docetaxel in both 2D and […]

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Glycoconjugated Metal Compounds: Cytotoxicity and Cellular Distribution

Cancer is the leading cause of death in Canada. Cancer patients suffer from the side effects (e.g., hair loss) of the chemotherapeutics, as they lack selectivity, killing both cancerous and non-cancerous cells. Thus, there is a need for more selective drugs. Cancer cells need sugar for fast growth, having high levels of glucose transporters to […]

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Identification des principales dynamiques de perturbations des vieilles forêts boréales résineuses

Les vieilles forêts sont des écosystèmes fournissant de nombreux habitats associés à une biodiversité spécifique ainsi que des services écosystémiques essentiels aux sociétés humaines. Les coupes forestières à échelle industrielle causent toutefois une perte et une fragmentation des vieilles forêts, ce qui interroge sur la durabilité de ces pratiques. Développer de nouvelles approches de sylviculture […]

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Séjour de formation en analyse métabolomique dans le laboratoire du Pr Jean-Luc Wolfender de l’Univeristé de Genève (Suisse)

Mon projet est focalisé sur la recherche de nouveaux métabolites bioactifs provenant de sources naturelles, plus spécifiquement de champignons, en particulier ceux du Nord du Québec. Cette région a été particulièrement négligée pour la recherche de nouveaux produits naturels et nous pensons que les organismes qui s’y trouvent produisent des métabolites spécialisés uniques en raison […]

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Phylogeographic analysis of susceptible and resistant Aspergillus fumigatus isolates from Manitoba

Aspergillus fumigatus is a widely distributed filamentous fungus found in soil and decaying organic material. It is also capable of causing serious respiratory infections in those with underlying health conditions, and it was named as a top-priority fungal pathogen by the World Health Organization. Recent global evidence demonstrated that agricultural antifungals contribute to clinical antifungal […]

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Harnessing Next-Generation Sequencing for Large-Scale Fungal Surveillance and Diagnostics in Sorghum

Project overview: Identification of fungal communities within the sorghum phyllosphere from symptomatic samples via Next-Generation Sequencing Sorghum is vital for food security in drought-prone areas of South Africa. However, fungal diseases such as leaf blight, anthracnose, and panicle blight significantly reduce yields and grain quality. With limited recent data, this project seeks to characterize fungal […]

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Ethnobotanical survey of Indigenous vegetables consumed in some Limpopo communities in the form of “food as medicine” and bioavailability of their phytonutrients

Indigenous leafy vegetables (ILVs) are the cheapest and easily accessible sources of important nutrients such as proteins, vitamins, especially the pro vitamin A and essential amino acids. Most of ILVs have long been known and reported to have many health properties through the presence of phytochemicals. Phytochemicals are bioactive, non-nutrient plant compounds in fruits, vegetables, […]

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