The Royal Botanical Gardens (RBG) in Hamilton, Ontario, face a challenge as Magnolia seedlings have been escaping from their arboretum and naturalizing in nearby forested ravines over the past 12–14 years. Although RBG staff suspect these populations stem from Magnolia kobus, the presence of various cultivars and hybrids complicates identification through morphological observation alone. To […]

SONA Nanotech is a world leader in the manufacturing of gold nanoparticles and applications thereof. Currently SONA has an anti-cancer technology that gently heats tumors from the inside using gold nanoparticles. The anti-cancer effect comes by virtue of cancerous cells being more susceptible to heat-induced death than healthy cells. Currently, SONA Nanotech’s gold nanoparticles require […]

My research project will be investigating the effects of climate change, through ocean acidification and warming, on the growth rate of a coralline algae species that is prevalent in arctic and subarctic oceans. Coralline algae take in calcium carbonate from seawater and form hard skeletons, similar to a coral reef. In doing so, they create […]

The proposed project aims to enhance the ability of Freeport Hospital’s Department of Physical Medicine and Rehabilitation to capture, integrate, and analyze key performance indicators (KPIs) in real time by developing a comprehensive data analytics program. This will involve identifying gaps in data collection, mapping relevant data points across clinical systems, and creating a live […]

Herein, we propose the lead optimization of novel antitubercular quinolone compounds targeting the DprE1 enzyme; an important enzyme in Mtb cell wall biosynthesis. The previously synthesised compounds exhibited sub-micromolar activity against the wild type (H37Rv) Mycobacterium (Mtb) strain. The lead compound in the series further exhibited activity against resistant fluoroquinolone Mtb strains and it binding […]

Artificial intelligence promises to dramatically accelerate preclinical biomedical research, yet ensuring it provides accurate and relevant information remains a challenge. Current approaches may fabricate references and often lack the context needed to fully address scientific questions. Consequently, AI has not been widely adopted for applications such as hit selection from biological screens or experiment design. […]

Les traits d’histoire de vie, ce sont des traits primordials qui déterminent la fécondité et la survie. La génétique, l’environnement et leurs interactions les affectent de grande ampleur. Mon projet met en évidence des traits d’histoire de vie des plantes : la dormance et la taille des graines. En utilisant des données climatiques, j’ai développé […]

Cystic fibrosis-related diabetes (CFRD) is a unique form of diabetes that differs from type 1 and type 2 diabetes. It affects almost 50% of patients with the genetic disease cystic fibrosis (CF) but its precise cause remains unknown. Our goal is to understand the root cause of CFRD by investigating changes in cells extracted from […]

L’ADN est le dépositaire de l’information génétique des organismes. Mais ceux-ci font face à des facteurs environnementaux susceptibles de causer des dommages à l’ADN, mettant ainsi en péril leur vie et leur patrimoine génétique. Parmi ces facteurs, les rayons UV jouent un rôle majeur. Au fil de l’évolution, les organismes ont développé un mécanisme de […]

Lors des missions spatiales, les astronautes perdent souvent du muscle en raison de la microgravité, ce qui pourrait être aggravé par une balance énergétique négative, c’est-à-dire consommer moins de calories que celles dépensées. Pour les prochaines missions, les agences spatiales considèrent la gestion de cette balance comme essentielle. Cependant, peu d’études ont exploré comment l’exercice, […]

In Canada every year, approximately 20% of the food produced becomes waste and food waste is Canada’s largest residual municipal solid waste category. Despite diversion strategies like composting, 28% of residential and 25% of industrial, commercial, and institutional solid waste is comprised of food waste and landfilled or incinerated. Food waste can be converted to […]

This research proposal aims to employ cutting-edge machine-learning tools to classify the a group of RNA molecules in heart cells and thereby unravel their function