Cereal grains are essential to human diets, providing vital nutrients and serving as key sources of carbohydrates and protein. With climate change posing challenges, identifying adaptable crops is crucial for global food security. Barley and sorghum stand out due to their resilience and nutritional benefits. They contain various phytochemicals, notably phenolic compounds, which offer health-promoting […]

De nombreuses pathologies et troubles dégénératifs sont caractérisés par l’accumulation de dépôts protéiques fibrillaires. Ces fibres amyloïdes se retrouvent dans plusieurs maladies, dont la maladie de Parkinson, d’Alzheimer et le diabète de type 2. Plusieurs mécanismes cellulaires contribuent aux voies cytotoxiques de ces protéines amyloïdogéniques, notamment la perturbation des membranes cellulaires. Le mécanisme de perturbation […]

Major depressive disorder (MDD) affects 20% of the population, with females twice as likely to develop it. Cognitive symptoms like negative cognitive bias (NCB) are resistant to treatment and understudied. Pilot data suggest sex differences in hippocampal activation and functional connectivity between brain regions in NCB. This is significant, as altered brain connectivity affects therapeutic […]

Le cancer de la prostate est le cancer le plus fréquent au Canada. L’histoire naturelle des cas diagnostiqués et de leur progression demeure inconnue. À date, aucun facteur de risque modifiable a été clairement identifié. Certaines études ont suggéré que la consommation de café et de thé serait protectrice contre le risque du cancer de […]

Viruses impact almost every aspect of human life, such as in carbon availability oceans impacting climate, food security in agriculture, and importantly in health. Humans are colonized by both benign and disease-causing viruses. Retroviruses, such as Human Immunodeficiency Virus (HIV), are a class of viruses that use reverse transcriptase (RT) to convert RNA-based genomes to […]

EPA and DHA are two important omega-3 fats that people mostly get from their diet or dietary supplements. The Omega-3 Index (O3I) reflects the amount of EPA and DHA found in red blood cells. A high O3I is linked with good health, while a low O3I is linked with higher risk of heart disease. Importantly, […]

The overarching goal of this project is to determine whether glacial mineral extract improves the overall health of skin cells. To do this, we will test the extract on human epithelial cells in petri dishes. More specifically, we will test whether the glacial mineral extracts help the cells to grow and study how the cells […]

Edible coatings have emerged as a promising alternative to traditional plastic packaging due to their biodegradability, minimal environmental impact, and ability to incorporate functional ingredients. Despite these advantages, most existing edible coatings suffer from poor mechanical properties and limited surface functionality, which constrain their industrial use and commercialization. Cold plasma (CP) has shown significant interest […]

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Our project aims to develop polymer-lipid hybrid nanoparticles (pLNPs) to enhance gene delivery to cells throughout the body, addressing two major challenges: ineffective release of genetic material inside cells and limited targeting of non-liver tissues. By incorporating a pH-sensitive material, our pLNPs are designed to improve the release of their genetic cargo within cells while […]

20/20 OptimEyes Technologies has developed a nanoparticle technology that can improve treatments for patients. We are moving forward into clinical trials for glaucoma, but we know we can improve other disease treatments with our technology. During this internship, our intern will evaluate other potential therapies where we could use our platform technology and build a […]

Our research team has worked with the Northern Alberta Cardiac Rehabilitation Program (NACRP) to develop an online, home-based cardiac rehabilitation program (“My Heart Coach”). This program provides exercises and educational activities consistent with current clinical practice guidelines. A potential opportunity for improvement in this program and others is the development of a woman-focused cardiac rehabilitation […]