Understanding the biodiversity ecosystem function relationships of herbivorous reef fish at the Hawai’i Institute of Marine Biology

Hawaiian coral reefs are extremely diverse and host a suite of endemic species. This diversity is a key aspect of their resilience. Fishing is an important aspect of Hawaiian culture, providing food and livelihoods for local people. Most of the fishing within Hawai’i is non-commercial and occurs in the near-shore, where herbivores make up 21% […]

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Exploring water-light interactions and protein dynamics during simultaneous environmental perturbations using near-infrared spectroscopy and aquaphotomics

This project will explore the interactions between water’s molecular structure and light, and use this knowledge to study the behaviour of proteins within the water sample. The intern will collect data using near-infrared spectroscopy (NIRS), which can provide insight into what a sample contains based on how different materials absorb light. Samples with a high […]

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Super-resolution microscopy of caveolin-1 dynamics in response to mechanical stress: caveolae, scaffolds and cell signaling

Caveolin-1 (CAV1) is a protein on the plasma membrane that forms cup-shaped structures caveolae, which flatten to protect cells under mechanical stress. However, the relationship between the caveolae and other CAV1 structures, scaffolds and dolines, in the process of caveolae formation and flattening is unclear. A challenge is to differentiate caveolae from scaffolds using conventional […]

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L2M – Targeting several intrinsic regeneration pathways in the context of neurodegenerative diseases

Treatments for neurodegenerative disorders represent an unmet medical need, affecting more than 50 million people worldwide. Through extensive research, we have identified two innovative therapeutic targets that have demonstrated promising effects in enhancing the regeneration and resilience capacities of neurons in animal models of Amyotrophic lateral sclerosis and Huntington’s disease. Our approach not only has […]

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Développement d’une nouvelle génération de composites bois-polymère

Le composite bois-polymère (CBP) est un matériau de construction fait de polymère chargé de particules ou fibres de bois. La popularité de ce matériau est grandissante, mais ses propriétés mécaniques le limite aux applications non-structurales. Le projet propose d’évaluer cinq approches qui permettraient d’élargir le spectre d’utilisation des CBP et d’augmenter significativement leurs propriétés mécaniques: […]

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NeuroCSF: development of a novel fMRI method to measure contrast sensitivity function in the amblyopic visual cortex

This research project centers on exploring the Contrast Sensitivity Function (CSF), a fundamental concept in visual perception that determines the perception of spatial frequencies at varying contrast levels. Existing CSF measurement methods relying on behavior are constrained by time and patient-related factors, necessitating an alternative approach. To address this challenge, we introduce the “neuroCSF,” which […]

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Estuarine reliance of juvenile salmonids in the Skeena River

Research on salmon in the Skeena River estuary in 2007 and 2013 quantified the abundance of different species of salmon in different locations of the estuary over time. These results indicate that the region where industrial development is proposed contained the highest abundances of Chinook and sockeye in both years surveyed, and coho in 2007. […]

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Comparative Analysis of Sexually Transmitted Infections and Antibiotic Resistance Genes in Wastewater: A Transcontinental Wastewater-based Epidemiology Study Between Canadian and Japanese Communities

It is estimated that more than 1 million cases of sexually transmitted infections (STIs) are acquired globally each day and significantly impact sexual and reproductive health. Existing STI outbreak surveillance methods rely largely on clinical reporting which can underestimate the scale of community outbreaks, primarily due to asymptomatic cases and patient test avoidance resulting from […]

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Etudes mécanistiques de réactions métallo-catalysées par électrochimie

Le projet consiste à étudier de nouveaux complexes métalliques en particulier à base de Nickel afin de pouvoir les utiliser dans le cadre de réactions catalysées. Cette recherche a pour but le développement futur de processus plus efficaces, plus économiques et plus verts pour la production de produits organiques utiles à la société. Le palladium […]

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Deploying GABA metabolism to boost plant immunity to phytopathogens: From fundamental research to practical application

?-Aminobutyric acid (GABA) is a non-protein amino acid that has recently been discovered to play an important role in plant-pathogen interactions. In this proposal, we will comprehensively investigate the potential of GABA metabolism to boost plant immunity against fungal and bacterial pathogens using tomato and Arabidopsis as model plant systems. The effectiveness of exogenous applications […]

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