Asset-Based Community Enterprise Development in Bolivia Year Two

This cross-sectoral research project will track the process of supporting four nascent community-based enterprises (CBEs) in indigenous communities in the Bolivian highlands, examining the complex interaction of factors that contribute to successful CBEs. The four cases will provide a test of an innovative “Community-Based Enterprise Development Model” (CBED Model) as a method to facilitate and […]

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Evaluating the viability of electroanaesthesia and chemical anaesthetic options in juvenile lake sturgeon (Acipenser fulvescens)

All five sturgeon species in Canada are considered at-risk. Conservation research on sturgeons often involves capturing wild sturgeon and performing procedures like tagging surgeries, so we can better understand their ecology in waters that are often impacted by human activities. In this project, we will work with our partner organisation, BC Hydro, to try to […]

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Hand and Eye-Tracking Feature Extraction for Biometric Machine Learning of Flight Simulator Operation

Our project seeks funding through the MITACS Globalink internship to introduce a revolutionary approach to pilot training by integrating virtual flight simulation and biometric machine learning. Dr. Michael Barnett-Cowan leads this cross-disciplinary initiative, utilizing his expertise in flight simulation and motion sickness to develop a sustainable, inclusive, and cost-effective flight training system. At the core […]

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Evaluation of dietary strategies to reduce methane emissions of dairy cows

The dairy cow industry is a significant contributor to emissions of the potent greenhouse gas methane because of anaerobic fermentation that occurs in every cow’s forestomach. The proposed research aims to contribute to development of dietary strategies to reduce methane emissions from dairy cows by at least 50% without affecting wellness markers and lactation performance. […]

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L’étude de la régulation métabolique des adaptations épigénétiques dans les cancers du sein triple-négatifs

Le cancer du sein triple négatif (CSTN) présente un pronostic défavorable, et une forte chimiorésistance. Les cellules du CSTN s’adaptent à la privation d’oxygène, aux carences nutritionnelles, et aux traitements à l’aide de reprogrammations épigénétiques. Les enzymes de remodelage de la chromatine orchestrent une réorganisation épigénétique en réponse aux fluctuations métaboliques dans les cellules de […]

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The mechanism(s) of antimicrobial activity of Kisameet clay

Kisameet Clay is a First Nations product of great interest due to its potent antimicrobial activity. Investigation of KC, as a potent inhibitor of bacterial and yeast growth, shows promise as a therapeutic agent. Work is in progress to identify the chemical components of KC responsible for this therapeutic activity. Work is in progress to […]

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Molecular Standards for AUC Validation and GMP Practices

The discovery of CRISPR-based gene therapy methods using viral vectors, and SARS-CoV-2 vaccines based on lipid nanoparticle formulations has revolutionized the field of personalized medicine, and promises revolutionary applications for curing cancer, genetic disorders, and other diseases on the molecular level. To facilitate the validation of new therapies, biopharma companies use analytical ultra-centrifugation (AUC) to […]

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La signalisation de l’Interleukine-15 dans les cellules myéloïdes

Les produits microbiens déclenchent la production d’une cytokine, l’Interleukine-15 (L-15), par les macrophages (Mf) et les cellules dendritiques (DC). Au cours de sa biosynthèse, l’IL-15 s’associe à son récepteur a (IL-15Ra) et est ” trans-présentée ” au complexe de récepteur ß?c sur les cellules cibles. Les souris déficientes en l’IL-15 et déficientes en l’IL-15Ra présentent […]

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Pediatric Cancer Drivers: From Target Discovery to Clinical Translation

This research cluster, a joint initiative between the Sorensen Lab at UBC and the Morin Lab at SFU with a number of key partners, involves a multidisciplinary approach to better understand the role of genetic changes in individual types of pediatric cancer, and how we might use this information to design better treatments for these […]

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Evidence synthesis to help contextualize the evidence to support innovation in physical activity promotion in Alberta

To ensure that PPPH priority projects are developed using the most up-to-date evidence and to increase the likelihood of project success, evidence synthesis will be crucial in facilitating a deeper understanding of community health issues, the contributing factors, associated health inequities, and appropriate interventions to improve health outcomes. The objective of this project is to […]

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Development of Microcystinase Enzymes and Immobilization into a Microcystin-Degrading Cartridge for Water Treatment.

The project consists of developing a device for degrading a harmful toxin produced during algal bloom in water supply. The cyanotoxin mycrocystin-LR is one of the major toxins produced by certain cyanobacteria that are present in large quantities in microalgal or cyanobacterial blooms. The benefits of this project for Naturia Technologies will be important since […]

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