The proposed project will determine how the Opto-mization Neuro-Visual assessment captures improvements in a patient’s vision over time and in response to treatment. To accomplish this, the Neuro-Visual assessment database will be organized into a library with data from all patients who completed the assessment, every time they completed the assessment, with a custom MATLAB […]

Our research project aims to contribute to capuchin monkey conservation in Brazil. These monkeys are struggling due to the loss of their natural habitats and the illegal pet trade. We are looking at how they use fallback foods (FBF) — things they eat when their usual food isn’t available — to survive. We will map […]

Les territoires qui alimentent les aquifères et la dynamique de renouvellement de l’eau souterraine sont encore peu connus, ce qui entraîne de grandes incertitudes sur la vulnérabilité de la ressource. Les objectifs de ce projet sont de tester de nouvelles méthodes pour 1) comprendre combien de temps l’eau souterraine a circulé avant de refaire surface […]

Important challenges remain around planning an ethical, justified, and accountable strategy for transitioning from emergency to long-term planning or closure of programs. Canadian Red Cross (CRC) aims to develop a practical guidance tool for closing humanitarian programs that will combine established operational practices with evidence based ethical considerations. This research will be qualitative in design […]

The proposed research project aims to investigate how Saccharomyces cerevisiae, a microorganism commonly used in the food and biofuel industry, responds to changes in temperature and manages to withstand high temperatures. Yeast cells face various types of stress as the environment conditions change, both in natural situations and during industrial processes. S. cerevisiae has developed […]

Triple negative breast cancer (TNBC) is a highly invasive and heterogenous disease that does not express oestrogen receptor and progesterone as well as the human epidermal growth factor receptor-2 and accounts for approximately 20% of all breast tumors. Its heterogenicity makes unlikely to reach the complete TNBC patient population with a single therapeutic agent. Therefore, […]

The most recent flood in Ahmedabad, India occurred in September 2013, when 50,000 people were displaced from low lying areas of the state. The World Bank report warns that the poor living in informal settlements, such as coastal slums in India, are the most likely to be killed or harmed by extreme weather linked to […]

The major problem with intervention for schizophrenia is the inability to treat all symptom categories (positive, negative, and cognitive) sufficiently. The need to test new novel therapies is crucial, which may prevent the onset of this debilitating disorder. Since intervention is limited to individuals at high risk, researchers have turned to animal models to test […]

ace à la propagation alarmante des bactéries résistantes aux antibiotiques, le développement de nouveaux antimicrobiens avec des modes d’action innovateurs est devenu une priorité mondiale. Parmi les différentes alternatives, les peptides antimicrobiens d’origine bactérienne comme les bactériocines sont très prometteurs. Ce projet s’intéresse particulièrement à cinq bactériocines produites par la bactérie Lacticaseibacillus paracasei qui ont […]

Cancer is associated with an accumulation of alterations in genes that confer the ability of cancer cells to grow uncontrollably. These alterations can contribute to increased deleterious function or loss of function of genes that normally regulate cell growth. Genes in our cells are organized on chromosomes which duplicate every time a cell divides. In […]

Promoting healthy living and reducing the burden of cardiovascular diseases are public health priorities in Canada and the United States. In recent years, the importance of measuring neighborhood contexts to address inequities in cardiovascular health has been highlighted. Many neighborhood indices have been utilized by academic researchers to explore the complex relationship between neighborhood and […]

Immunotoxins (ITs) are representing a subset of antibody drug conjugates where the synthetic toxin is replaced by a bacterial protein toxin. Major drawback is related to the immunogenicity of the protein not allowing repeated application. Consequently targeted human cytolytic fusion proteins (hCFPs) have been developed to replace the foreign protein toxin by a human apoptosis […]