An alternative liquid-driven pumpless micromixer for efficient therapy encapsulation in lipid-based nanoparticles

Our project focuses on developing a new device to create nanosized particles called lipid-based nanoparticles (LBNs) that can carry substances like genes, drugs, and proteins. LBNs have been successful in COVID vaccines and cancer treatments, but developing these therapies is challenging and requires specialized knowledge and equipment. To address this, we aim to create a […]

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Biomolecular Structure Analysis to Accelerate Development of New Vaccines and Monoclonal Antibodies

Manufacturing of consistently high quality products is the commitment of pharmaceutical industry. To achieve this, new products must be thoroughly tested and the results meet government-approved product specifications. Improving existing and adopting improved analytical technologies for product testing ensure the production of safe and effective products. This is particularly critical for the manufacturing of biologic […]

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SARS-CoV-2 Vaccine Strategies

As the SARS-CoV-2 virus mutates over time and variants emerge, it is crucial to stay ahead to keep the public safe. This research aims at capturing new variants that emerge and test them against the current therapies and vaccines in place as well as develop the next generation of vaccines and therapeutics to keep the […]

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Evaluating Participant Satisfaction and Results Sharing in Clinical Trials

Randomized clinical trials (RCTs) are considered the gold standard for evaluating bio-medical interventions. Their results can have important impacts on clinical practice and the development of scientific knowledge. Often recruitment of trial participants is one of the most challenging aspects of successfully conducting a trial. If participants are appreciated, and involved in the communication of […]

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Investigating the Effects of High-Intensity Interval Training Based Multimodal Prehabilitation on Inflammatory and Immune Markers in Patients with Non-Metastatic Non-Small Cell Lung Carcinoma – A feasibility study

Lung cancer is a significant health concern worldwide, and a common type called non-small cell lung carcinoma (NSCLC) is responsible for many cases. Surgery is the preferred treatment for early-stage NSCLC, but it can lead to complications after the operation, affecting patient recovery. In addition, inflammation before surgery has been linked to worse outcomes in […]

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Novel plant-based formulations for bladder health

Bacterial cystitis (BC) is a common painful inflammatory disease of the urinary bladder due to an infection. Even with antibiotic treatment, BC continues to have significant negative impacts of patients’ quality of life due to pain and risk of recurrence. Altheda Wellness Innovation Inc. (Altheda) is a Maritime´s based biotechnology company that specialized in the […]

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Genotypic variation in Candida spp. isolates from recurrent vulvovaginal candidiasis

Vulvovaginal candidiasis (“yeast infections”) affect 75% of women at some point in their life. Approximately 10% of them will experience recurrent yeast infections, which have considerable emotional and economic ramifications and require prolonged antifungal treatment. Despite the prevalence of recurrent yeast infections, we lack an understanding of the human immune system and microbial population factors […]

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Contextual Momentary Assessments of the Auditory Environment by Wearers of Hearing Aids

We would like to investigate the use of hearing aids in real life environments. Retrospective questionnaires are often subject to memory errors and recall biases. In order to obtain more accurate momentary evaluations of sound and noise, our proposed research involves asking participants to complete real-time evaluations in the laboratory and in their everyday environments. […]

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Assessing the incidences of positive and negative behaviour and interactionbetween stray dogs and the community of Campo Largo, Brazil.

A special group of stray dogs in Brazil known as ‘community dogs’ has been the centre of interest for scientific researchers. These community dogs may hold the key to controlling stray dog populations around the world, as well as mitigating disease transmission between animals and humans. My proposed project will look at the different behaviours […]

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Virtual Mental Health Services for Women At-Risk for Homelessness: Accessible and Free Psychotherapy

Women who have experienced homelessness encounter several barriers to escaping poverty. These women often experience limited economic independence and accompanying mental health issues that contribute to perpetuating their experiences of poverty. While psychotherapy could contribute significantly to this population’s wellbeing, marginalized women often have significant difficulty accessing psychological care despite their increased need for support. […]

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The effect of providing a rest period to surplus dairy calves without unloading from the trailer during long distance transportation

Few studies have investigated how rest period impact behavioral, metabolic, and clinical indicators of health and welfare of surplus dairy calves during long distance transportation. This project aims to fill these knowledge gaps and determine if unloading calves from the trailer for a rest period will mitigate the impact of transport. Results from this study […]

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Characterization of long-term eating behaviors (~15 years) in patients who have undergone bariatric surgery and eating habits likely to lead to weight regain.

The project aims to improve the pharmacovigilance and the report from the adverse events derivative from the drug use for treatment of heart failure. This will occur through the analysis of reported adverse events compared to those not reported throughout the years. In addition, factors associated with reported adverse events, especially fatal ones, will be […]

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