Myocardial infarction is among the most prominent causes of death worldwide. Following cardiac injury, changes in the composition of the extracellular matrix trigger inflammatory and fibrotic responses. Particularly, left ventricular remodeling and cardiac fibrosis are characterized by pathological glycosaminoglycan (GAG) production and ECM rearrangement, which contribute to cardiomyocyte death and subsequent heart failure. Additionally, chondroitin […]

The overarching objective of this proposal is to develop and validate a new, robust and reproducible 3D culture system that supports the clonal growth of primary sources of normal and malignant human epithelial cells and that is suitable for commercialization by STEMCELL Technologies who will partner in its development. The work will systematically address 3 […]

This project aims to develop sprayable coatings to prevent the prevent the attachment of bacteria on tables, door handles and other countertops. This will be obtained by modifying the surface with natural materials (such as vitamin B5 mimicking polymers and cellulose nanocarriers) that can deter bacterial attachment upon contact. The spray coated surfaces will sense […]

Recent advances in wearable devices have allowed athletes to monitor some determinant factors of their sport performance. In addition, they can be used to develop real-time 3D avatars of people to compete with them during dynamic activities. Kinetyx recently developed insoles with multiple sensors that can be worn within a shoe while performing many activities. […]

Rapid advancements in biotechnologies made possible novel studies to tackle chronic diseases such as breast cancer, or provide new insights into the role played by gut bacteria in a variety of chronic conditions. Data generated by biotechnologies comes with many analytical challenges: high number of candidate biomarkers measured compared to the number of patients, correlations […]

La litteratie alimentaire repose sur un ensemble d’attributs incluant les connaissances et les competences alimentaires ainsi que le contexte environnemental menant a des choix alimentaires favorables. Ce concept s’est particulierement developpe dans les programmes en milieu scolaire. Les camps d’ete rassemblant chaque annee des milliers de jeunes, demeurent aussi un environnement propice pour promouvoir les […]

Microplastics (MP), defined as any plastic polymer particles

Les végétaux demeurent de nos jours une source incontournable de molécules bioactives pour le développement d’agents thérapeutiques novateurs. Par contre, l’étude et l’utilisation des molécules d’origine végétale sont souvent limitées par leur manque de solubilité dans l’eau et leur faible biodisponibilité. Pour surmonter ces limitations, l’ajout de groupements polaires sur les molécules appelé dérivatisation est […]

This project is in response to an immediate market opportunity that shows an increasing demand for pulse-based flours as a substitute for animal protein and or for gluten-free diets. A strong red-orange color in products containing lentil flour is a current market demand. We will establish important characteristics in lentil varieties under field conditions, as […]

Skin diseases such as psoriasis and eczema are common and cause discomfort in skin lesions. Psoriasis is a chronic disease with cycles of unknown triggers. Currently treatments for psoriasis are very limited. A special bacterium-produced compound called benvitimod has demonstrated effects on treating both psoriasis and eczema by suppressing inflammation and promoting cell migration. However, […]