Antimicrobial resistance (AMR) occurs when antibiotic drugs and products stops working, making it difficult to treat infections and diseases which could lead to further health complications and death. Therefore, development of antibiotic products is needed to control the increasing cases of AMR. Medicinal plants are a great source of natural antibiotic compounds to make antibiotic […]

Often fractures don’t heal properly or large defects must be repaired in the bone due to accidents or disease. The drugs and treatments that are currently used to repair fractures are only partially effective. Mesentech Inc has developed a new drug that has shown a strong effect on bone formation in rats. In this project, […]

Plant based or vegan meat applications in the marketplace is experience a large market push, as demand for vegan products increases. To produce vegan sausages, casings are typically produced out of seaweed polysaccharides (e.g., carrageenan). However, this has limitations as clients are demanding increased criteria, such as locally grown or made from local Saskatchewan ingredients. […]

One approach that is commonly used to treat chronic condition is self-management interventions. Self-management refers to the daily “tasks that individuals must undertake to live well with … chronic conditions” (Adams et al., 2004). To help people with chronic conditions develop the skills needed to manage their conditions, several self-management interventions have been created. Many […]

Neurodegenerative diseases represent one of the largest healthcare burdens in Canada. However, there is limited understanding of how the complex biological factors affect the development of neurodegenerative diseases, thus the era of precision medicine has not to come to treat them yet. Here, we take focus on bioenergetic disruption as a shared risk factor of […]

Cannabinoids are synthesized and accumulate in Cannabis plant hairs called glandular trichomes, which are particularly abundant on female flower buds. Cannabinoid content and composition vary dramatically among Cannabis strains, with two general groupings distinguished: marijuana strains, defined by high THC and low CBD levels, and hemp strains containing low THC and high CBD (or low […]

Understanding and predicting brain activity is the main objective of computational neuroscience. Neuronal cells are the building blocks of the brain and responsible for electrical signaling and cognitive ability. Recent studies indicate that another cell type, called astrocyte, plays an important role as well. These cells have been proposed to interact with neurons and modulate […]

La voie Hippo est une voie de signalisation intra-cellulaire régulant différents processus tels que la prolifération et la différentiation cellulaire. Il a été démontré que la voie Hippo est impliquée dans le développement et la physiologie de l’utérus chez différentes espèces, dont la souris. Ses rôles dans la physiologie utérine bovine sont toutefois méconnus. De […]

The overarching objective of this proposal is to develop and validate a new, robust and reproducible 3D culture system that supports the clonal growth of primary sources of normal and malignant human epithelial cells and that is suitable for commercialization by STEMCELL Technologies who will partner in its development. The work will systematically address 3 […]

This internship will contribute to the market research and go-to-market strategy development of the Marine Way app, a citizen science mapping mobile application that will help combat the global ghost gear problem. The resultant outcome of the internship is expected to contribute to the establishment of a company and the future publication of the mobile […]

Internationally, school food programs (SFPs) are one of the most successful drivers of improved health, education, and economic growth. Yet, Canada is among the minority of countries without a nationally harmonized SFP. This project involves the creation of research briefing notes on key areas of impact of SFPs to support the Coalition for Healthy School […]

PARP inhibitors are an FDA-approved treatment for breast, ovarian and prostate cancers. This project aims to develop 3 new classes of PARP inhibitors, 2 of which can target multiple pathways with a single drug, helping to prevent resistance to the PARP inhibitors and enabling the combination of 2 drug treatments without the added side effects […]