Apport de l’ergonomie à la prévention des cancers professionnels dès la formation (CAP)

Le cancer professionnel, une cause de mortalité fréquente en France et au Canada, atteint de façon préférentielle certaines catégories d’emploi, pour lesquelles ce sujet doit être abordé dès la formation. Les apprentis sont particulièrement exposés aux agents cancérogènes et leur âge implique une exposition prolongée: 25% d’entre eux sont en contact régulier avec au moins […]

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Antifouling Performance of Graphene-based Coatings in Varying Flow Conditions

Marine biofouling, which is the growth of organisms on ocean infrastructure, is a widespread problem with substantial economic and environmental costs. This project undertaken by the intern will develop dynamic tests of a novel graphene-based antifouling coating designed by Graphite Innovation & Technologies (GIT). The dynamic tests involve generating water flow over the coating surface, […]

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Molecular You – Clinician Review Module UX Design

This project is a collaboration between the Emily Carr Institute of Art and Design and Molecular You. Molecular You are a health-tech start-up on a mission to help everyone live longer healthier lives using a new type of digital health experience that can spot early warning signs of chronic disease and tell you exactly what […]

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Disinfection efficacy of Far-UVC light in a healthcare facility

UV light is known for its antimicrobial properties. In this project, we expect to use a proprietary lamp which will provide a specific light that will target bacterial, fungal and viral strains commonly found in health care facilities. Results of the project will have a direct impact in the sterilization of areas with a high […]

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The fate of neutrophils and role of monocytes in sterile inflammation

Our immune system Is designed to protect us from harmful agents. It must initiate a rapid potent inflammatory response to eliminate invading pathogens. Although similar to the eradication of pathogens, the inflammatory response can also occur following a sterile injury and is required for tissue repair and wound healing. This includes trauma, ischaemia-reperfusion injury, autoimmunity […]

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Establishing a world-class biophysics platform that will enable and accelerate the discovery of leads for launching drug-discovery programs and biotech start-ups

Challenge: The most critical step in discovering future medications is the identification of the initial hit compounds (“leads”) that interact with target proteins and which have the desired properties. The search for and validation of potential lead compounds is a major challenge for launching drug discovery programs as this process requires highly specialized expertise, expensive […]

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Predictive microsimulation model for knee-OA progression and cost-effectiveness of earlynon-pharmacological therapies to improve long term patient outcomes

The proposed study has three objectives: Objective 1. Develop KOA microsimulation model: To develop and validate a Knee-OA population-based microsimulation model (POHEM-KOA) using the previously developed POHEM-OA model. Objective 2. Perform cost-effectiveness analysis of non-pharmacological therapies for KOA: To use POHEM-KOA in conducting a cost-effectiveness analysis of treatment strategies, including exercise therapy and weight reduction, […]

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Regulation of N-type calcium channel activity by Opioid receptor-like receptor – a novel mechanism to eliminate morphine tolerance

Prolonged morphine treatment is known to cause an up-regulation of ORL1 receptors in the spinal cord (12, 13), which in turn is believed to contribute to the development of morphine tolerance by altering ?-opioid receptor mediate modulation of N-type calcium channels. Indeed, ORL1 antagonists can reverse the development of tolerance, and ORL1 knockout can mediate […]

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Health in HIPPY Homes: Exploring the pathways and barriers to wellbeing of refugee mothers during resettlement and the COVID-19 pandemic, and the role of HIPPY in fostering household health and resilience.

The Health in HIPPY Homes project seeks to explore refugee mothers’ and families’ health during resettlement in Calgary, Alberta, Canada, and the various factors that affect their wellbeing during this period. Additionally, we are interested in better understanding the potential impacts that participating in the Home Instruction for Parents of Preschool Youngsters (HIPPY) program has […]

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Predicting Treatment Response to 1st-Line Pembrolizumab in Highly Expressing PDL1 Advanced NSCLC Patients using Artificial Intelligence Models

Late-stage lung cancer patients with non-small cell lung cancers who demonstrate high levels of PDL1 expression have better outcomes when placed on a combined treatment program of both immunotherapy and chemotherapy. There is a subset of patients that respond well to pembrolizumab, an immunotherapy drug, alone as an initial treatment path, but there are no […]

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