Building capacity in support of wastewater-based epidemiology to aid public health decision-making in southwestern Ontario

Novel coronavirus disease 2019 (COVID-19) is an acute respiratory disease induced by SARS-CoV-2. To date >1,000,000 deaths have been reported worldwide. Although testing capacity has expanded, Canada still faces challenges to realizing wider scale testing. A promising alternative to large-scale population testing in Canada may lie literally beneath our feet in our municipal sewer systems. […]

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The PAC App: Evaluating a Nationally Promoted Physical Activity App

In order to improve the health of Canadians, ParticipACTION developed the ParticipACTION App (PAC app), an incentivized, physical activity (PA) promotion and tracking app. The PAC app aims to increase the amount of PA and decrease the amount of sedentary activities for all Canadian. The PAC app was launch in February of 2019, and currently […]

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Marine resilience in the Anthropocene: understanding the adaptive capacity of marine social-ecological systems to change

The ocean is experiencing drastic declines in biodiversity due to the cumulative impact of human activities, including habitat loss, resource exploitation and fossil fuel emissions. These declines in species abundance and diversity have dire consequences for coastal communities whose economic and social systems depend upon healthy oceans. While global analyses of human impacts on marine […]

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Analyse des impacts de la disponibilité en eau sur la croissance, le transport de sève (sapflow) et la nutrition des arbres

Les changements climatiques auront des effets importants sur la forêt canadienne. L’augmentation de la température combinée à des précipitations stables pendant la période de croissance, amèneront une diminution du contenu en eau des sols forestiers et augmenteront la probabilité de sécheresse intense dans le futur. Malgré quelques études récentes, les impacts sur les forêts au […]

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Electroplated Phosphonate Quaternary Ammonium Antimicrobials for Corrosion, Wear and Antimicrobial Resistant Metal Surfaces

We are proposing to use a rapid, safe and green electroplating process to adhere antimicrobial phosphonate quaternary ammonium materials onto receptive metal surfaces. Pathogenic infections are responsible for approximately 60% of all hospital acquired infections. In order to help stop the spread, high contact surfaces such as bed rails in hospitals, door knobs etc. require […]

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Investigation of IL-5R? expression on ILC2 as a target for Benralizumab

A newly identified group of cells termed type 2 innate lymphoid cells (ILC2s) have been discovered in the past decade. Increasing evidence supports the view that ILC2s play a central role in driving the cellular changes in the airways of asthmatic subjects. ILC2s are increased in severe asthmatics with uncontrolled inflammation despite being on the […]

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COVID-19 Infection and Epithelial Cell Markers

Covid-19 has emerged as a major health concern in 2020, with a mortality rate of 11%. Covid-19 is due to a new coronavirus, SARS-CoV-2, which enters the human body through a receptor called ACE-2 in the airway. Asthmatics are usually at increased risk for viral infections, which exacerbated their asthma symptoms, however early clinical studies […]

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Understanding Stress Signaling in Childhood Cancers: reactive oxidant species (ROS) signaling pathways

The Sorensen laboratory-based Childhood Cancer Research Program is specifically focused on elucidating the genetic and biological determinants of the metastatic process in childhood cancer. Metastatic disease remains the single most dominant driver of adverse outcome in most childhood cancers, particularly in childhood sarcomas. There are two basic strategies in the program for studying metastatic disease […]

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Géochimie de résidus non magnétiques de la mine Lac Tio

À la mine Lac Tio (Québec), exploitée par Rio Tinto Fer et Titane (RTFT), les rejets miniers génèrent parfois du nickel au-delà des seuils permis dans les eaux de drainage. Alors que RTFT prévoit de retraiter des rejets existants pour en extraire leur valeur économique résiduelle, il est nécessaire d’évaluer de quelle manière le nouveau […]

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Assessment of freshwater mussel species at risk translocations due to river infrastructure works: A case study of Argyll Bridge and the Grand River

This project seeks to understand the impact of translocation on freshwater mussel communities due to river infrastructure works in the Grand River, Ontario, Canada. We will determine the recovery of mussel communities post-translocation, and place them into context with similar translocations from across the region. The work will involve new empirical data on mussel recovery […]

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