A Community-Orientated “Skills for Success” Research Project

This research internship project with Ms Birdsall shall investigate and develop a functional plan for a corporate social investment (CSI) model that integrates: (i) Douglas College’s Skills for Success recommendations with the industry partner’s current CSI program and future Social & Labour Plan [SLP] obligations; and (ii) the capabilities and potential resources of the South […]

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QU02 MRI: a new window on mitochondrial dysfunction in Alzheimer’s disease

This project seeks to develop new methods for imaging oxidative and vascular function in the brain. The methods under development are based on widely available MRI hardware, which will make them feasible for use in future clinical drug trials, an application that is of interest to the partner organization CQDM. Before the approach is ready […]

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Risk classification over time for individuals who have diabetes

This project/research is based on creating AI models that assist in determining blood glucose levels in individuals that have been diagnosed with Diabetes and classify changes in their risk-levels over a period of time. This research will be carried out by Ian Ho, student at Queen’s University pursuing his Bachelor’s in Applied Science – BASc, […]

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Microchemical techniques to evaluate priority contaminant sources along the migration routes of Chinook (Oncorhynchus tshawytscha) and Coho Salmon (Oncorhynchus kisutch)

Adult Chinook and Coho Salmon migrate to a variety of marine regions around the North Pacific. Along these migration routes, the contaminants they encounter and consume will vary. These returning salmon are consumed by humans and Southern Resident Killer Whales, and the health risk they pose will be dependent on their migration routes and diets. […]

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Improved Phenotyping of Macrophages Using Cell Line Models, Gene Expression Signatures, and Protein Secretion Data

Chronic obstructive pulmonary disease (COPD) is a 3rd leading cause of death, which decreases lung function due to irreversible airway obstruction. Lung immune cells, such as macrophages, play an important role in the disease progression. However, researchers don’t fully understand their diversity and functions. Models of macrophages are useful to better understand patient macrophages. We […]

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Standardization and optimization of saliva sample processing for SARS-CoV-2 detection without nucleic acid purification

The SARS-CoV-2 outbreak, which started in Dec. 2019, has so far not been contained due to unpreparedness and unsuccessful development of antiviral drugs against SARS-CoV-2. In response to this pandemic, we propose development of a diagnostic assay based on saliva samples. We will also standardize virus collection procedure and inactivation steps to reduce the turnaround […]

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Bacterial proteolytic function in inflammatory bowel disease

Differences in the composition of bacteria within the gut have been found in patients with inflammatory bowel disease (IBD) and healthy people. In addition to this, bacterial functional differences may also contribute to inflammation in IBD, but it is difficult to determine whether these changes are cause or the consequence of disease. Proteases, which are […]

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The role of regulatory T cells in blood during acute heart transplant rejection

Patients receive heart transplants as a life-saving measure after heart failure; thus, ensuring the success of the transplant is of utmost importance. Rejection is a primary cause for heart transplant failure, and consequently, patients must take drugs that suppress the immune system to prevent rejection. However, these drugs are highly unspecific and cause serious side […]

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