3D-printed personal protective equipment can provide a locally-sourced manufacturing network to address shortages for Canadian front-line workers during the COVID-19 pandemic, however little is known about the harmful germs that can live on 3D-printed material. Certain metals-ions are known to have anti-microbial properties and can be incorporated into 3D-printed plastics. We will study the anti-microbial […]

The novel SARS-Coronavirus-2 becomes activated and is infective after interacting with the human TMPRSS2 enzyme, as it primes the virus to enter and hijack lung cells for viral replication. By designing drugs using a strategy that has shown success in inhibiting enzymes structurally similar to TMPRSS2 and understanding the exact shape of this enzyme in […]

words) The Canadian Red Cross (CRC) has been at the forefront of providing support to the COVID-19 response in Canada. The Global Health Unit (GHU) at CRC is providing health-related technical and operational support to CRC in its efforts to combat the impact of COVID-19 in Canada. To optimize the CRC operations, the GHU is […]

Récemment et avec l’apparition du SRAS-CoV-2, la demande, tant au niveau personnel que professionnel, pour des produits textiles conférant une protection contre ce virus a littéralement explosée. La compagnie FilSpecMC a développé une gamme de fils techniques innovants pour la production de produits textiles médicaux qui possèdent des propriétés antibactériennes. Dans ce projet, nous désirons […]

This proposal aims to develop essential technologies for rapid and accurate SARS-CoV-2 antibody test in serum and droplet blood using microflow cytometry immunoassay (MCIA) for on-site testing. The test will assess levels of immunoglobin G (IgG) and immunoglobin M (IgM) antibodies produced in response to SARS-CoV-2 exposure. Unfortunately, none of the antibody testing tools currently […]

The current COVID-19 pandemic has posed many challenges to healthcare professionals as they deal with managing the primary disease and it many complications. The proposal aims to develop, test, and validate an assay to detect quickly immune checkpoint targets in T cells in peripheral blood with high specificity and sensitivity using a diagnostic device, CytoFind, […]

Correction of misaligned teeth requires orthodontic braces treatment. Cone-beam computed tomography (CBCT) has been routinely used in orthodontic diagnosis and treatment planning in recent years. Its three-dimensional capability to view images has a significant advantage over traditional 2D X-rays. However, CBCT typically delivers more radiation than conventional dental 2D X-rays. As children and adolescents are […]

The SARS-CoV-2 outbreak, which started in Dec. 2019, has so far not been contained due to unpreparedness and unsuccessful development of antiviral drugs against SARS-CoV-2. In response to this pandemic, we propose strategies for the development of novel antiviral agents against a number of known viral targets using in-silico modeling and laboratory testing to rapidly […]

Deep mechanized mines can be harsh work environments. In addition to the dust and potential noxious gases, workers are frequently exposed to high heat and high humidity conditions for extended periods of time. Studies suggest that an individual’s ability to maintain a safe body temperature decreases with age, thereby increasing the risk of heat-related injury. […]

As of May 1st, 2020, over 3.2 million cases of COVID-19 have been confirmed, resulting in over 233,000 deaths globally. This project aims to provide an alternative vaccine for the prevention and treatment COVID-19 in high risk individuals, mainly the elderly and immunocompromised, who do not respond well to tranditional vaccination. Using a single viral […]

In Canada, about one third of children aged 5 to 17 years are overweight, and 12% have obesity – a number that has tripled over the past 50 years. Childhood obesity is associated with increased risk of several comorbidities, including type 2 diabetes, low self-esteem, depression, and cardiovascular disease. In an era of personalized medicine, […]

La COVID-19 est causée par un nouveau virus, le SARS-CoV-2 et frappe durement la population mondiale. Cette maladie soulève de nombreuses questions, dont celle de savoir si l’immunité développée par les personnes ayant guéri de la maladie permet de neutraliser efficacement le virus et d’assurer une protection à long terme. Dans le cadre de ce […]