Presently, there are almost 100,000 people in Canada with COVID-19, the disease caused by the SARS CoV-2 virus, and almost 7000 have died. Although an effective vaccine is the ultimate goal, it is a long way off. To slow the spread and reduce the medical, social, and economic burdens, new treatments are needed. To find […]

Hirschsprung disease (HSCR) is a deadly birth defect affecting 1/5000 children. These children are missing innervation from the enteric nervous system (ENS), resulting in severe constipation and a high risk of bacterial translocation into blood causing premature death. Surgery to remove ENS-devoid bowel is generally life-saving but many children with HSCR continue to have severe […]

Some of the bacteria present in healthy lungs protect the lung against harmful germs. Studies have shown that people with lung diseases often lack these “good” bacteria in their lungs. Our team has been demonstrated that breathing polluted air causes lung inflammation, which can make it hard to breathe, especially for people who have lung […]

In order to help deal with COVID-19 pandemic, there is an urgent need for development of fast, reliable, and sensitive tests that will be capable of detecting IgG and IgM proteins directly in people’s blood. Our novel test for detection of IgG and IgM proteins in the blood offers several major advantages compared to other […]

Pathogenic infections are responsible for approximately 60% of all hospital acquired infections. In order to help stop the spread, high contact surfaces require chemical additives that sense and respond to the presence of pathogenic bacteria quickly, and neutralize their threat. We are proposing a new form of antimicrobial that can be used as safe, green […]

The projects will involve the modifications of a small automated ventilator (breathing machine) suitable for use in pandemics and underresourced settings (outside hospital, in patient transport, small hospitals), especially suited to patients with severe lung disease. Partner organization will be able to improve the design of the current ventilator to make it better suited for […]

Dental procedures generate a large quantity of airborne droplets. With the concern that COVID-19 transmits through respiratory droplets, dental personnel are at high risk of being exposed to the virus if an asymptomatic patient comes to their clinic. However, limited studies have been performed on the characterization of aerosols generated during dental procedures, how far […]

Scientists have been interested in the effects that microorganisms have on their host plants for over a century, however, recently researchers have been able to better tackle these questions with the advent of new technology. In particular, beneficial microorganisms associated with roots can increase crop resiliency against disease, pests and extreme weather events, making this […]

Le baseball au Québec est pratiqué par 33 000 joueurs et joueuses à travers la province. La fédération de baseball Québec est celle qui régit la pratique du sport dans la province. Le projet de recherche sur les facteurs individuels de la performance chez les jeunes garçons et les jeunes filles permettra d’assurer le développement […]

This project aims to develop SARS-CoV-2 genomics tools to apply to the tracking of COVID-19 in municipal wastewater. Detection of SARS-CoV-2 genetic material in wastewater has been used to estimate prevalence of the virus in the corresponding community. This has the potential to be a relatively inexpensive early warning system that is complementary to testing […]

The current project will assemble a library of molecules known as single-chain variable fragment (scFv) antibodies to treat COVID-19. The scFv antibodies will neutralize the SARV-CoV-2 coronavirus that causes COVID-19 by targeting its spike (S) glycoprotein. ScFv antibodies offer numerous advantages compared to other treatment alternatives such as small-molecule drugs and monoclonal antibodies, and are […]

Effective anti-viral therapies are required to treat individuals infected by the SARS-Cov-2 virus, the causative agent of COVID-19. So far, only repurposed drugs have been investigated as treatment to fight SARS-Cov-2 infection. The goal of the project is to use our custom yeast-based screening platform in collaboration with the artificial intelligence algorithms of InVivo AI […]