Process Analytical Tools, Flow Cytometry and Raman Analysis for Cell Viability Studies

The objective is to develop an in-line Process Analytical Technology (PAT) tool to monitor viability and biomass levels at the fermentation stage bacterial organisms. The Master student will be engaged in the development of the PAT tool for deployment into a state-of-the-art vaccine manufacturing facility. The student will use benchtop tools such as flow cytometry […]

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Part 2 (extension): Long-term evaluation of corticosteroid-releasing formulations to suppress implant device- related foreign body reactions and fibrosis

Implanted medical devices have dramatically improved the lives of millions of patients worldwide. However, in many cases, the body’s immune system rejects these devices and encapsulates the implant in fibrous scar tissue. This reaction is most detrimental to sensors for continuous monitoring and treatment of chronic conditions such as diabetes and those of the central […]

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Decentralized Deep Radiomics: Scaling up the discovery of prognostic and predictive cancer imaging biomarkers from routine clinical data across a network of hospitals

Genetic advances over the past 10 years have led to the development of several targeted therapies for lung, breast and colon cancer. However, there are a number of factors that limit the optimal use of these innovations, including the high cost of the organizational process associated with molecular testing, and their late use in the […]

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Validation of a weighted wearable training system for hockey skating

ROKET GEAR is a Canadian start-up that has developed a wearable training system for hockey skating. The system consists of adding weights strategically placed on the leg so that skaters can actually strength train while skating. As a result, the training system allows athletes to increase their effort during skating and to build strength in […]

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Auditory spatial and memory processing in the blind

Early loss of vision is accompanied by widespread cross-modal changes in the brain, in that ‘visual’ areas of the brain show responses to nonvisual stimuli. This raises the possibility of using the reorganization associated with vision loss to investigate how auditory events may be encoded and retrieved from memory. The proposed project will examine the […]

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Rapid detection of Salmonella in fresh produce using a paper-based microfluidic device based on recombinase polymerase amplification and lateral flow immunoassay

Salmonella is one of the most common causes of foodborne illnesses and 50% of its recent outbreaks are associated with fresh produce. To protect the safety of fresh produce, rapid, cost-effective and easy-to-use detection methods are necessary for government laboratories and food industry to frequently monitor Salmonella level. The gold standard bacteriological culturing and polymerase […]

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Social Influence and performance in a simulated clinical scenario and evaluation of the validity of simulation for team training

The complexity of modern healthcare requires teams of professionals to work together to identify gaps in care. Failures of the healthcare team mean that patient safety and healthcare outcomes are compromised. This series of studies will explore how cognitive load and stress influence obedience to authority, team performance and ultimately patient safety. The outcomes will […]

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Collection and transcription of a corpus of aphasic speech for the development of a prototype of an intelligent communication aid application

Aphasia is an impairment of language caused by an injury to the brain. Word finding difficulties often accompany aphasia and can persist even after intensive speech therapy, having a negative impact on the person’s social participation and quality of life. Today’s communication aids can improve the ability to effectively communicate but findings from focus groups […]

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Real world testing of online cognitive training and rehabilitation programs

With an aging population on the rise, the prevalence of cognitive decline is expected to increase substantially. Goal Management Training® (GMT) and the Memory and Aging Program® (MAP) are cognitive interventions that have been studied extensively and applied clinically to address these needs. Although previous research has demonstrated efficacy of the in-person versions of both […]

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