The intensity and frequency of heat waves is increasing. The effects of this on agricultural pests is poorly understood. Insects have a remarkable ability to adapt to unfavourable conditions, and this resilience can be inherited. This study springboards a novel collaboration to study whether a newly discovered method of DNA transmission across generations, extra chromosomal […]

Our Mitacs intern, Paula Renee Boldut will be assisting with the launch of a new Co-op and carrying out research for her Master’s degree into challenges and strategies to achieve food sovereignty in rural and urban communities The project sponsor, the provincial non-profit group Food Producers Forum (www.foodproducersforum.com), is a six-year old non-profit group developing […]

Ce projet met en valeur le potentiel des EPS issus de souches probiotiques en tant que biomolécules d’intérêt thérapeutique. Nous serons en mesure de démontrer leur efficacité contre les pathogènes responsables des infections, tout en validant et consolidant leurs propriétés anti-inflammatoires sur des modèles cellulaires gingivaux. L’extraction, la purification et la caractérisation approfondie des EPS […]

This project aims to assess how drug clinical trials in Canada approach the inclusion and exclusion of people who are pregnant, lactating or who have the potential to become pregnant. This is necessary because pregnant and lactating individuals have been historically excluded from clinical trials, limiting knowledge on treatment safety and efficacy for this population. […]

High-stock density farming is a common strategy in the poultry industry to support the upgrowing global consumption of meat. However, this type of intensive practice favors the transmission and spread of infectious diseases such us the Infectious Bursal Disease (IBD), which outbreaks are massive and have devastating economic consequences. Current vaccines against IBD have variable […]

The proposed research project will focus on investigating alterations in the salivary proteome of patients undergoing hematopoietic stem cell transplantation. By tracking these changes, we aim to understand how the transplantation process affects the salivary glands and saliva composition, and how this alteration relates to the oral complications experienced by these patients. The study will […]

This project focuses on improving the design of post-surgical bras for people recovering from breast cancer surgery. In an earlier phase of the research, patients shared their experiences wearing a specially designed surgical bra after surgery. Their feedback highlighted issues with comfort, fit, gaps and how the bra made them feel during recovery. Phase Two […]

The emergence and dissemination of antibiotic resistance is an escalating public health issue that requires immediate interventions. Among the essential agents in combating bacterial infections are peptide-based antibiotics. These naturally occurring or synthetic molecules exert potent antibacterial activity through various mechanisms such as membrane disruption, inhibition of cell wall synthesis, and immunomodulation. Despite their therapeutic […]

More lung transplants are taking place across the world and in British Columbia. A type of life support, an artificial lung machine called extracorporeal membrane oxygenation (ECMO), has made it possible for patients who are more severely ill to receive a lung transplant. More and more patients are doing better with ECMO since it was […]

Contrary to popular belief, children under five aren’t naturally active all day. In fact, most don’t get enough movement to support healthy development, and this matters, because over two-thirds of their waking hours are spent in childcare. Yet, many early childhood educators (Educators) receive little to no training in how to promote physical activity through […]

L’intestin joue un rôle central dans l’absorption des médicaments et des nanoparticules, et constitue donc une cible clé pour le développement de systèmes d’administration orale. Cependant, afin d’optimiser ces approches, de réduire les coûts et de limiter les expérimentations animales, un modèle in vitro biomimétique du tractus gastro-intestinal humain est nécessaire. Or, les modèles actuels […]

Pathogenic alleles in human asparaginyl-tRNA synthetase (NARS1) cause heterogeneous genetic disorders collectively known as NARS1 diseases. NARS1 disease is an early onset disease, and few children reach adulthood. No NARS1 specific therapies are available, and treatments remain supportive. The molecular and cellular consequences of most pathogenic NARS1 alleles remain unknown. We will investigate NARS1 mutations […]