Evaluation of the clinically management weight-loss program at Wellness Institute at Seven Oaks Hospital

Many Canadians are overweight or obese which increases their risk for various diseases. However, many weight loss approaches don’t work. The objective of this project is to evaluate a weight loss program managed by doctors, dietitians and exercise specialists that focuses on improving healthy eating habits and increasing physical activity at the Wellness Institute. The […]

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Scientific and Clinical Hub for Orphan Drug Development

With rapid and cost-effective genome sequencing becoming the norm, many causal mutations for inherited genetic diseases are being rapidly determined. The discovery of new genes for inherited diseases is enabling rapid genetic and chemical genetic platforms to be used to discover drug targets and drugs/drug-like molecules as potential treatment options for patients with inherited diseases. […]

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Functional Proteomics to Inform Targeted Therapy for Head and Neck Cancer

To ensure effective cancer treatment, it is vital to match the drug with the molecular characteristics of the patient’s tumor. This research project is focused on developing functional diagnostic assays that may be used eventually in the clinic to stratify patients for targeted therapies. The project will provide a unique opportunity for the interns to […]

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Canadian Partnership for Research in Immunotherapy Manufacturing Excellence (CanPRIME)

Cancer remains the leading causes of mortality worldwide. While treatments are available, existing chemotherapies and radiation therapy have limited success due to secondary effects on healthy cells, resulting in adverse side effects in patients. Over the past 5 years, we have witnessed the development of new and promising cancer therapeutics that stimulate and awaken the […]

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Microalgae for the production of plant specialized metabolites of interest

Algae-C is a company specialized in algal biomass production. It enables on-site production of algae for a wide variety of sectors (aquaculture, nutraceutical, cosmetic and biofuel). To date, many fuels, pharmaceuticals and cosmetic products are extracted from plants. These valuable plant natural products (PNPs) are often produced in low quantities in plants and extraction methods […]

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Environmental productivity patterns of the Salish Sea: trends, impacts, projections

Pacific salmon are important from ecological, economic, social and cultural perspectives, but many species in the Salish Sea have seen drastic decrease in marine survival rate in recent decades, likely linked to reduced survival of the young stages of salmon due to a combination of environmental, food web changes, and human impacts. This activity will […]

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Biological Evaluation of Antimicrobial Materials

Bacterial infections spread from one person to another person by means of a simple “touch” of contaminated surfaces in healthcare units. These infections have become untreatable to most existing antibiotics, thereby accounts for significant mortality rate. Polyamyna Nanotech is developing new antimicrobial coatings that prevent spreading dangerous bacterial infections in hospitals and health care units. […]

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Discovery of antibodies against challenging membrane protein targets using microencapsulation-assisted rare clone selection

Antibody-based medicines are playing an ever increasing role in the arsenal of treatments of many diseases, from cancer to obesity to Alzheimer’s. Cell surface proteins, called membrane receptors, are considered key therapeutic targets in many of these pathologies, yet targeting them with antibodies has proven to be a challenge. Amgen British Columbia is dedicated to […]

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Impact zootechnique, économique et génique de l’âge au sevrage des caprins

Même si une forte croissance de la production laitière caprine au Canada est observée au cours des 20 dernières années, la productivité des fermes laitières caprines dépend de plusieurs facteurs liés à la génétique et à la régie de troupeau. La nutrition des chevrettes laitières et des méthodes d’élevage des chevrettes ont été identifiées comme […]

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The effect of phyto-cannabinoids on osteoclast differentiation and function

The recent legalization of marijuana in Canada opens the opportunity to study in detail the effects of cannabinoids on human physiology. This academic-industry initiative will combine resources to isolate compounds from cannabinoids to study their effects on bone cells. Specifically it will examine the effects of cannabinoid compounds on how the destructive osteoclasts form and […]

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