Sea cucumbers are found in both benthic areas and deep seas and have been used as a source of food and drug for decades. During the past decade, several scientific research initiatives explored various species of sea cucumber. However, not much research has been done on Atlantic species. As an emerging fishery in Atlantic Canada, […]

The wild blueberry is an important crop in the Canadian Atlantic provinces with 140 million kg of fruit being produced in 2016 with a farm gate value of $155 million. However, gray mold disease caused by Botrytis cinerea can cause substantial damage with 20% crop losses being reported. This study seeks to the genes and […]

Ibuprofen is at the top of the World Health Organizations listing of essential medicines. As such, Ibuprofen is commonly consumed in nearly all countries. Considering Ibuprofen is poorly degraded by the human metabolism, wastewater tends to be a significant source of Ibuprofen in the environment. Concern has arisen over the past decade due to Ibuprofens […]

Adenosine is a naturally occurring molecule that is found in many living systems that can be used as to slow rapid heartbeat and other ailments. Its efficient use as a medication depends on adenosine receptors present on many tissues within the human body. This family of receptors consist of four subtypes with the A1AR subtype […]

Pancratistatin (PST) has been shown to selectively eliminate human cancer cells, but has not been used extensively in clinical trials due to its low availability in nature. Recently, different forms of PST have been synthesized and have demonstrated anti-cancer activity. These synthesized PST molecules have been tested on prostate, pancreatic, osteosarcoma and colorectal cancer cells. […]

Alzheimer’s disease (AD) is a neurodegenerative disorder that is difficult to detect early before apparent manifestations of cognitive decline. Current detection methods rely on expensive and hardly accessible imaging techniques (PET scans). Optina Diagnostics developed a new camera as well as innovative image processing methods to propose a non-invasive test to identify the presence of […]

Au Québec, 5 000 tonnes de homard sont pêchées annuellement en Gaspésie et aux Îles-de-la-Madeleine. Les risques pour les pêches maritimes liés au transport de matières dangereuses, tels que les hydrocarbures, augmentent. Notre projet vise à optimiser le suivi en usine de la qualité du homard vivant, par trois biotests qui renseigneront sur l’état de […]

In the intestines of people living with inflammatory bowel diseases (IBDs), the balance of beneficial bacteria is shifted. Instead, the intestine is overloaded with potentially harmful bacteria – a phenomenon known as dysbiosis. This shift in bacterial populations is believed to be among the key contributors to the onset of inflammation observed in IBD patients. […]

The bobolink (Dolichonyx oryzivorus) is a migratory songbird that is currently a species at risk in Canada due to steep population declines. Because bobolink nest on the ground in pastures, hayfields, and other grassland-type habitats, nest success and abundance may be influenced by various environmental factors. Our goal is to understand whether these factors directly […]

Heart failure is a complex cardiovascular disease with increasing global burden while the prognosis for patients remains poor. Risk factors and the type of heart failure differ between men and women. These differences can be due to sex – referring to biological differences – or gender – referring to social differences. In our project we […]

Alzheimer’s is the most common form of dementia which worsens over time. Current therapeutic against Alzheimer’s disease provides only symptomatic treatment. This limited effectiveness provides us with an opportunity to direct our research efforts towards developing new agents to prevent or retard the disease. Studies have shown that very small amount of tetrahydrocannabinol (THC), a […]

More than half of all women suffer from some form of pelvic floor disorder over their lifetime, with pelvic organ prolapse and urinary incontinence being the two most common presentations. High impact physical activity is one risk factor for the development of pelvic floor disorders, where it has been postulated that repeated impacts experienced chronically […]