Study of Corner Brook Pulp and Paper Limited (CBPPL) byproducts and potential uses for food production

Overall this study aims to determine feasibility, parameters, and processes related to improved utilization of selected byproducts resulting from Corner Brook Pulp and Paper Limited (CBPPL) operations. The proposed activities and ideas relate to monitoring and understanding the nature of the composition of the mill’s production of wood ash over time, determining the suitability, feasibility […]

Read More
Defining the role of gut microbiota in intestinal stem cell development and inflammation

Neonatal necrotizing enterocolitis (NEC) is one of the most common and deadly disorders of the gastrointestinal tract in preterm infants, accounting for the second highest percentage of neonatal deaths. Although the underlying disease mechanisms are still unclear, the increased incidence of NEC has been associated with excessive antibiotic use during pregnancy. Newborns become exposed to […]

Read More
Application d’une analyse de sélection au comportement de jeu des joueurs de jeu vidéo

Notre but est d’améliorer la capacité des compagnies à concevoir et entretenir des jeux vidéo multijoueur en utilisant les théories développées par les écologistes pour comprendre le comportement des animaux (par exemple pour comprendre pourquoi les lions préfèrent chasser en groupe plutôt que seul). Nous analyserons les tactiques de jeu utilisées par les joueurs dans […]

Read More
Predicting climate change resilience of mine site reclamation in Yukon’s boreal region: from site and ecosystem classifications to biological response

Research problem: Reclamation practices in regions known to be undergoing rapid climate change must consider what adaptive measures could be implemented to maximize short-term reclamation success and long-term resilience of reclaimed sites. Objectives: I will investigate how a multi-scale ecological classification system can be used to predict regeneration success of different forest tree species at […]

Read More
The Sherbrooke Personalized Cancer Avatar Model Initiative: A Feasibility Study of Treatment Guided by the Combination of DNA Profiling and Next-Generation Medical Avatars in Patients with Advanced Kidney Cancer

We recently developed a rapid and cost-effective pre-clinical technology that is well suited for precision medicine –the ex ovo chicken embryo ChorioAllantoic Membrane (CAM) assay. Our goal is to perform a pilot study that combines tumor genotyping data and the use of personalized CAMavatars, to predict drug sensitivity in renal cancer patients and to test […]

Read More
Development of skin-humanized mouse model for psoriasis

The objective of my research is to generate self-assembled artificial skin and humanized mouse model for study of various skin diseases. The artificial skin is made using human derived skin cells, which are then grafted to mice. This humanized mouse model is most similar to the environment in the human body, and the self-assembled artificial […]

Read More
Generation of decidua specific decorin knockout mice.

Dysfunctions of the placenta leads to a serious pregnancy associated disease of the mother called preeclampsia (PE) and certain forms of fetal growth restriction (FGR) that are hard to treat or prevent. Our laboratory has shown that overproduction of decorin, a molecule made by the pregnant uterus, leads to placental defects resulting in PE and […]

Read More
Dinosaur bonebed amber: paleoecological and paleoenvironmental reconstructions

Amber, or fossilized tree resin, is a natural trap that provides a valuable source of palaeontological data on insects in ancient ecosystems. The chemistry and composition of the amber itself can also be used to explore which trees produced each amber deposit, and what conditions these trees lived under. Western Canada contains multiple amber deposits […]

Read More
Establishment of a Pressure Ulcer Biobank from Spinal Cord Injury Patients

Pressure ulcers (PUs) are a major health problem in people with spinal cord injuries (SCIs). PUs increase hospital admissions, with 25% of SCI treatment cost linked to PU management. Currently, treatment is limited and new therapeutic options are required. Wound fluid from PUs is invaluable for researchers as it allows a detailed study of the […]

Read More
Self-Assembly of Amphiphilic Metal-Organic Polyhedra for Membrane applications

Metal-organic polyhedra (MOPs) are discrete molecular capsules formed by coordination of metal ion and organic linkers. They possess a nanoscale cavity which can have potential applications in gas storage, separations, drug delivery or sensing. To enhance their usage for practical purposes, these materials need to be translated into membranes. MOP-polymer composites where MOPs are blended […]

Read More