Obesity, type 2 diabetes (T2D) and heart diseases have skyrocketed. Controlling glucose usage and insulin balance can substantially decrease the morbidity and improve the quality of life in affected individuals. Dysfunctional insulin action and energy balance in the body is associated with excessive non-adipose fat storage, particularly in the liver, and elevated circulating lipids, which […]

Chemotherapy is currently the most effective approach for treatment of advanced cancer. However, chemotherapeutics do not differentiate between malignant and normal cells, and lead to serious side effects. Recent findings indicate that a substantial proportion of cancers, as distinct from normal tissue, are deficient in an enzyme called methylthioadenosine phosphorylase (MTAP). This provides a unique […]

Hops (Humulus lupulus) flowers are most famous for imparting the bitter taste and aroma to beer. Hop flowers produce essential oils that contain many different plant compounds, which impart the characteristic taste and aroma of hop plants. However, how the production of these oils is regulated is not fully understood. The establishment of the craft […]

PROTACs are bifunctional molecules that allow the elimination of target proteins in the cells. Despite the advantages of this early field, the area of small molecules PROTACs presents some drawbacks, in particular, the long and tedious syntheses of the central linker. Secondly, the variety of those linkers is quite scarce, as poly-ether or alkyl chains […]

Les PROTACs sont de nouvelles molécules thérapeutiques ayant pour but de soigner certaines maladies grave comme les cancers. Ces composés sont des molécules linéaires constitués de trois composants principaux : une extrémité permettant de repérer la cible, une autre extrémité permettant de causer la dégradation de cette cible, et enfin un linker reliant les deux. […]

City trees and forests provide numerous ecosystem services (e.g. cleaner air, cooler environment, recreation) to human society but they are increasingly threatened by the changing climate, urban sprawl, invasive pests and diseases. This is particularly the case for Eastern Canadian cities that see the need to replace a large proportion of their trees killed by […]

City trees and forests provide numerous ecosystem services (e.g. cleaner air, cooler environment, recreation) to human society but they are increasingly threatened by the changing climate, urban sprawl, invasive pests and diseases. This is particularly the case for Eastern Canadian cities that see the need to replace a large proportion of their trees killed by […]

The coastal wet mixedwood forests of Nova Scotia are globally important for lichen biodiversity, but several lichen species are now declining or endangered. This is concerning for forest managers, because forest companies may be subject to penalties if they inadvertently destroy the habitat of an endangered species. The causes of lichen declines are not fully […]

Bend Beauty is a Halifax based company involved in the research, development, and marketing of oral natural health products for use in skin-care and anti-aging. Bend’s core product, Anti-Aging Formula, is a mixture of the active ingredients fish oil, borage oil, lutein, zeaxanthin, and vitamin D3. An eight-week human clinical study demonstrated this product increases […]

Bend Beauty, Inc. has developed an oral natural health product marketed for use in antiaging and photoprotective skincare. This product, a supplement called Bend Skincare Anti-Aging Formula, is a mixture of six active ingredients: fish oil, borage oil, lutein, zeaxanthin, and vitamin D3, which has been clinically demonstrated to increase the skin’s resistance to sunburn. […]

Le présent projet s’inscrit dans la continuité des missions dans lesquelles la Fondation MIRA s’est illustrée en proposant ici d’intégrer puis d’incrémenter les recherches concernant les effets du chien d’assistance sur l’enfant avec troubles du spectre autistique (TSA). Ce projet se divise en deux études distinctes venant se pencher sur deux thématiques non investiguées jusqu’à […]

Ce projet est réalisé en collaboration avec la Fondation Mira. Notre objectif est d’étudier les effets du chien d’assistance sur l’enfant avec troubles du spectre de l’autisme (TSA). Le projet se divise en deux études se penchant sur des thématiques non-investiguées jusqu’à présent. Au cours de la première étude, sera étudiée l’évolution de la dynamique […]