A Novel Combination Therapy to Target Primitive Acute Myeloid Leukemia Cells

Modern molecular targeted therapies have shown promise in treating some blood cancers, but a cure remains elusive for most acute leukemia patients. This is largely due to the survival of some leukemic cells that possess unique properties and can cause treatment failure or relapse, warranting identification of new, distinct targets for improved therapies. In collaboration […]

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The anti-Helicobacter pylori properties of probiotic lactobacilli secretomes

Helicobacter pylori is a bacterium that causes 65% of gastric ulcers and cancers worldwide. Current snit- H. pylori treatments often fail because the bacteria have become resistant and they have serious side effects. We are looking into using molecules produced by bacteria called lactobacilli that are a natural component of the human gastro-intestinal flora to […]

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Effective knowledge translation of evidence-based best practice for healthy lifestyle behaviours

The proposed research will support the effective knowledge translation of evidence-based best practice information related to healthy lifestyle behaviours (such as physical activity, healthy eating, smoking cessation, stress management, and alcohol moderation). Over a two-year period, the post-doctoral fellow will create a series of knowledge translation tools (including web- and smartphone-based applications) that can be […]

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Effective knowledge translation of evidence-based best practice for healthy lifestyle behaviours – Year two

The research supports the effective knowledge translation of evidence-based best practice information related to healthy lifestyle behaviours. Over a two-year period, the post-doctoral fellow will create a series of knowledge translation tools that can be used in the effective primary and secondary prevention of chronic disease through lifestyle behaviour modification. Our proposed initiative will capitalize […]

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Testing of Cannabinoid Oil Extracts in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model of Multiple Sclerosis (MS)-Induced Neuropathic Pain (NPP)

The cannabinoid class of medications are widely used to treat disease or alleviate symptoms such as spasticity and pain associated with MS. However, the exact molecular mechanisms by which they exert their beneficial effects remain unknown. Recent research and clinical trials demonstrated that cannabinoids may not only alleviate the symptoms of MS, but may also […]

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Assessing the Utility of a Commercial Mobile EEG in Detecting Age-Related Differences in the Brain – Year two

The world is aging rapidly and healthy cognitive aging a major healthcare priority. Thus, a better understanding of how the brain changes with normal aging versus pathology is required. Advancements in wearable technologies may allow the assessment of brain function with greater ease, accessibility, and at a lower cost, as compared with traditional neuroimaging techniques. […]

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Reducing birdstrike risks at airports by integrated pest management of insects

Problem: Airports are increasingly important, both economically and socially, for the movement of people and goods. A major risk faced by airports is the potential for collisions between aircraft and birds (bird strikes). Bird strikes are dangerous and expensive, with costs including the repair of damaged aircraft and of closed runways delaying flights and leaving […]

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