Biobased products, mostly derived from plant biomass, have the potential to improve the sustainability of Canada’s natural resources and environmental quality while competing economically. Plant biomass, composed primarily of cell walls and modification of cell wall properties has the potential to improve biomass conversion to biobased products such as biofuels. Progress towards achieving this goal […]

In Brazil, inequities in accessing healthcare are linked to socioeconomic disparities. Poor and middle-income countries – like Brazil – bear the highest burden of cancer morbidity and mortality; yet typically do not have structured screening programs. My research aims to evaluate an innovative program in Brazil for screening breast, cervical, prostate and skin cancer. To […]

Le virus de l’infuenza (la grippe) est dépendant des enzymes présentes chez l’hôte pour être infectieux. La collaboration entre les laboratoires de Dr Martin Richter, Dr Éric Marsault et Dr Richard Leduc à l’Université de Sherbrooke a permis de développer et d’optimiser des inhibiteurs qui bloquent l’activité de ces enzymes essentielles au virus. Ainsi, dans […]

Le projet proposé vise le développement d’un nouveau produit de santé naturel pour le traitement de l’herpès labial. Le stagiaire sera en charge du développement de la galénique du produit en accord avec la règlementation de Santé Canada. Ce produit comportera différents extraits naturels notamment de Cornus sericea connu pour son action directe sur le […]

La compréhension du système nerveux, plus particulièrement du cerveau, suscite beaucoup d’intérêt depuis toujours. Décoder l’organisation cellulaire ainsi que les modes de communication neuronaux demeurent par contre un énorme défi. La microscopie optique jumelée au développement de sonde fluorescente a permis de faire d’énorme progrès en neuroscience. Avec la venue de l’optogénétique et la capacité […]

For platelet transfusion, it is necessary to prepare, store and maintain platelet concentrates. Platelets concentrates have a short shelf life and must be conserved at ambient temperature – ideal for bacterial growth. Bacterial contamination of platelet concentrates represents the major cause of morbidity and mortality in transfusion. However, the bacterial agent causing these effects remains […]

Endospores of thermophilic, sulfate-reducing bacteria (TS-SRB) are widespread in the marine rare biosphere and have been proposed as model organisms for studying microbial dispersal. Hot subsurface oil reservoirs could potentially be ‘deep biosphere’ source environments for these organisms, whereby TS-SRB are transported into the cold seabed through natural hydrocarbon seeps. Thus these endospores could be […]

Despite the high prevalence of Inflammatory Bowel diseases (IBD) in industrialized countries, particularly in Canada, the mechanisms controlling these debilitating gastrointestinal pathologies remain poorly understood. IBD is though to arise from an uncontrolled immune response to the intestinal microbiota, inducing a persistent inflammatory reaction in the gut. Death of epithelial cells and loss of epithelial […]

En 2009, un nouvel agent pathogène est apparu dans une plantation d’arbres de Noël au Québec, il s’agit du champignon Delphinella balsameae qui cause la brûlure des pousses de sapin. À ceci s’ajoutent les divers champignons causant le rouge des aiguilles qui cause des dommages économiques importants et dont la biologie est aussi peu connue. […]

In order for Canadian industry to continue to meet the high demand for energy they must adhere to the social and environmental pressures to reclaim and restore the extraction sites to fully functioning ecosystems, and to offset environmental destruction when appropriate. Recent changes to Canada’s Fisheries Act in 2012, have enshrined offsetting strategies as a […]

Our brain is constituted of billions of neurons gathered in networks and communicating between each other through electrical impulses. It is possible to impact on this nervous activity through stimulations of various origins including electric, magnetic or acoustic. Indeed, neurostimulation can artificially induce signals within the nervous network, but also modulate the existing signals by […]

The goal of this proposal is to clarify the reasons for an increased burden of serious bacterial infections caused by two common pathogens: Haemophilus influenzae and Streptococcus pneumoniae in Canadian First Nations. Methodology includes comparative analysis of the critical parameters of naturally acquired immunity against these pathogens in adult First Nations individuals living in two […]