Cancer cells are known for their unique capacity to survive and grow in a low oxygen tension environment in the middle of a poorly vascularized solid tumor. This adaptation, which is central to the tumorigenesis process, is mediated by precise cellular mechanisms allowing the regulation of gene expression. Thus, the development of small molecules to […]

Rates of obesity are continuously rising despite efforts to decrease them. The purpose of this study is to show that obese but fit individuals are protected from many adverse health conditions such as metabolic syndrome, insulin resistance, type-2 diabetes, high blood pressure, and cardiovascular disease as the result of being physically active. This study is […]

White pine blister rust is a serious disease of pine, an ecologically and economically important forest species in Ontario and the Maritime Provinces. In western Canada, this pathogen has virtually eliminated pine as a commercial species and the disease now threatens eastern Canada. Endophytes are fungi that live in the leaves of various plants including […]

Tens of thousands of chemicals are present in the Canadian environment. The impact of those chemicals on wildlife and other components of the environment is often poorly quantified. The intern will develop a method for assessing the potential damage of a class of emerging contaminants, flame retardants, to avian brains. Specifically, the intern will examine […]

This internship will involve licensing three smooth muscle cell lines. I will be working with the cell lines and growth factors to promote blood cell formation in vitro (not within a living organism). The company will then have the cell lines licensed, and we will then work to assemble a kit for commercial use. IThe […]

Algae are microorganisms present in all aquatic environments with the ability to grow using sunlight as energy source. This ability can be harnessed to produce biomass for various purposes of industrial interests such as biofuel, animal feed, nutrients, etc. This project seeks to improve the productivity of an algal growth facility while reducing energy costs […]

This project will look at how eating hemp foods, specifically hemp oil and hulled hemp seeds, daily for four weeks will impact human health. The Mitacs interns will be involved in a human clinical trial which will measure the impact of hemp food consumption on blood fatty acid profiles and cardiovascular disease risk factors, in […]

The hog industry in Manitoba is a very efficient means of converting grains and pulses into high quality protein. Fresh pork is a healthy and nutritious source of protein, yet demand remains static. One of the main reasons cited by consumers for not choosing pork is the absence of good taste in modern pork. The […]

Les designers de jeu vidéo accordent maintenant beaucoup de liberté à leurs joueurs qui coopèrent et combattent pour les différentes ressources dans de vastes univers virtuels en constante évolution. Les comportements observés dans les jeux vidéo multi-joueurs s’approchent de plus en plus à ceux des animaux dans leur écosystème. Ainsi, l’ensemble des joueurs d’un jeu […]

Acute myeloid leukemia (AML) is a blood cancer with very poor prognosis, especially for patients older than 60 years of age. This is in part because of the severe toxicity of medicines available. Less harmful medicines are needed to better treat older patients. Therapure Biopharma Inc. has chemically linked the standard toxic chemotherapy medicine called […]

Disturbed sleep is a common feature of chronic obstructive pulmonary disease (COPD) ranking third in frequency behind shortness of breath and fatigue. Actigraphy is a non-invasive technique for monitoring sleep at patient’s own home and is an attractive alternative to expensive laboratory based tests like polysomnography. Unfortunately, no studies have tested the accuracy of actigraphs […]

Manufacturing of consistently high quality products is the commitment of the pharmaceutical industry. To achieve this, new products must be thoroughly tested and the results meet government-approved product specifications. Improving existing and adopting improved analytical technologies for product testing ensure the production of safe and effective products. This is particularly critical for the manufacturing of […]