Identification and characterization of new antimicrobial chemical series

Antibiotic resistance represents a major health problem for society. With the expanded use of antibiotics, microorganisms have developed various mechanisms of resistance to overcome the effects of once highly effective agents. There is therefore an urgent need to identify new therapies to counteract resistant strains. The intern will design and identify new drugs that are […]

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Photonic Quantum Computing for Machine Learning

In the recent years, the advances of machine learning, and more precisely deep learning, have lead to incredible progress in areas such as computer vision, speech recognition and natural language processing. Training algorithms based on deep neural networks can take a huge amount of time and computing resources. The first generation of quantum computers currently […]

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Development of Applications of Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging

Funded through a series of NSERC partnership grants, Cubresa Inc. have been working with the applicants to develop technologies for pre-clinical imaging for positron emission tomography (PET) imaging and PET friendly radiofrequency (RF) coils for magnetic resonance imaging (MRI) of small animals. To date, our collaboration has played a direct role in Cubresa being the […]

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Development of Applications of Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging – Year two

Funded through a series of NSERC partnership grants, Cubresa Inc. have been working with the applicants to develop technologies for pre-clinical imaging for positron emission tomography (PET) imaging and PET friendly radiofrequency (RF) coils for magnetic resonance imaging (MRI) of small animals. To date, our collaboration has played a direct role in Cubresa being the […]

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Creation of candidate glucocerebrosidase PET imaging agents

Mutations in the enzyme glucocerebrosidase (GBA1) are the most common genetic risk factor for development of Parkinson’s disease (PD). PD is characterized by the buildup of abnormal protein deposits in the brain, followed by progressive loss of neurons and behavioural symptoms. Numerous studies have noted a correlation between reduced GBA1 activity and increased levels of […]

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Synthesis of an irreversible inhibitor of Pol?

One aspect of modern drug development involves understanding how enzymes function in terms of the progress of certain diseases in humans. This MITACS project involves the synthesis of small-molecule labels that can bind to a specific enzyme of interest, so as to better understand the mode of action of this enzyme as related to the […]

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Étude des contraintes mécaniques des films de MgO : mise en évidence de gradients diminuant la symétrie locale par la spectroscopie TERS

De nos jours, les ordinateurs, les téléphones cellulaires et beaucoup de gadgets électroniques voient leur taille diminuer de plus en plus au fur et à mesure que les années passent. Actuellement, la technologie de ces dispositifs électroniques est basée sur le silicium. Or, le silicium atteint les limites de sa performance plus la taille des […]

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Bipolar Membranes for Electrochemical Technologies

Bipolar membranes (BPMs) are already a commercially relevant technology as they are used in the electrodialysis process, that is, they are used to convert salt water into industrially useful acid and base products. Recent research, on the laboratory scale, has demonstrated that bipolar membranes also have useful applications in water splitting technologies that produce hydrogen […]

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Dipolar depletion : study of a field tunable colloid-polymer solution

In a colloid-polymer mixture, the addition of non-adsorbing polymer can control the magnitude as well as the range of an effective attraction between micron-sized colloidal particles. In such a system, various phases, including network-forming gels, can be observed. With tunable interactions, such systems could also be used for the studies of phase transition kinetics. An […]

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Self-Assembly of Redox-Active Receptors

The discovery of new chemicals and materials with unique optical and structural properties is the driving force behind the manufacturing of the innovative devices for electronic, sensing and medicinal applications. In this research project, novel compounds will be synthesized and incorporated into self-assembled cages as building blocks on a large molecular scale. These cages will […]

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Understanding the nanostructure of organic photovoltaics

In light of our dramatic environmental situation, we are faced with implementing carbon-neutral power sources. The sun offers a nearly endless supply of energy that can be converted into consumable power with the use of photovoltaics. While current photovoltaics are rather efficient, they are expensive to manufacture and install. A new branch of photovoltaics, organic […]

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