Hybridization of exosomes with liposomes for nucleic acid delivery

Nucleic acids (DNA and RNA) have tremendous therapeutic potential, as recently shown by the development of messenger RNA vaccines against COVID-19. To fulfill their function in a patient, nucleic acids need to be encapsulated inside lipid-based nanoparticles (LPs), such as liposomes, but their synthetic nature leads to clearance by the immune system. This hampers nucleic […]

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Tourism the Chinese way: Impacts on ethnic minority Bailivelihoods in Dali, China

Around the world, tourism is having important and often drastic effects on the environment, minority cultures and livelihoods. This study focuses on the impacts that tourism is having on the culture and livelihoods of an ethnic minority group in southwest China—the Bai, whose population was 1.9 million in 2010. I will complete fieldwork in Dali, […]

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Safe Reinforcement Learning for Robot Manipulation

In recent years, reinforcement learning has shown great promise in solving sophisticated decision-making problems and has also demonstrated impressive results in robotic settings since it provides robots with novel skills without tedious modeling from human engineers. The objective of this research project is to develop a pipeline that autonomously generates a control policy for a […]

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Dynamic Simulation for Data-Driven Logistical Control of Iron Ore Material Streams

The Canadian iron industry will benefit from increasingly streamlined data to support operational decisions, particularly as their steelmaking clientele is transitioning toward carbon-neutral steel production. The iron ore required for carbon-neutral steelmaking is especially high grade, in accordance with the DRI-EAF steelmaking route. Key operational decisions include the formation and depletion of stockpiles for different […]

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Design and Implementation of an External-Cavity Laser (ECL) as a Tunable Coherent Source for Optical Communication and Sensing Applications Using Hybrid Integration

FONEX Data System Inc. is developing solutions to address the challenges that telecommunication service providers face in upgrading their access networks to sustain the growth in data traffic. A critical component of the solutions is low cost widely tunable laser modules. In this internship project, a novel laser source is proposed based on external cavity […]

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Plasma activated mist: Characterization and application efficacy

As the demand for healthier and ‘clean label’ food products is ever increasing, there is a need to develop novel food processing methods to address the risks associated with food safety while ensuring sustainability. Cold plasma activated water (PAW) and plasma activated mist (PAM) are gaining attention for potential applications in food products as a […]

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Entraînement d’un agent conversationnel pour les procédures internes

Koïos Intelligence est à la source de l’agent conversationnel Olivo qui vise à offrir une expérience interactive, guidant l’utilisateur au travers des processus de prévente, de vente et d’après-vente pour tous les types d’assurances. Bien que l’outil soit dans un état avancé tant au niveau de la conversation écrite qu’orale, et ce aussi bien en […]

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Development of nonlinear models of bolted joints for the identification of damping mechanisms through friction in gas turbines

Bolted joints are the most common interface in PWC’s gas turbine aeroengines and are believed to be a significant source of structural damping in the system. However, very little is known about the actual mechanisms at play in the joints. By conducting a systematic bolted flange research program, experimental data on bolted joints and engine […]

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Reaction-diffusion equations and hydrodynamic limit of interacting particle systems

Consider a physical system comprising a substantial quantity of particles that dynamically interact with each other over time. Since the number of particles is large, an explicit description of the microscopic behavior of the system becomes effectively impossible. An approach to understanding how these systems behave is to look at certain observables on a macroscopic […]

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Post Harvest Antimicrobial Treatments of Cannabis sativa

In order to maintain the quality and safety of dried cannabis, it is essential to control microbial contaminants through post-harvest irradiation. This research study focuses on the identification of optimal dosages for effectively reducing fungal pathogens in dried cannabis using customized Cathode Ray Tube (CRT) technology, which employs a basic form of electronic beam (e-beam) […]

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Development of an in planta soybean transformation method

This research project aims at establishing a cheap and simple alternative genetic transformation method for soybean termed in planta. Three in planta methods, named (i) tissue-culture independent callus and adventitious buds generation (TCICABG), (ii) sonication and in vivo selection/regeneration (SivSR) and (iii) in vitro embryonic axis sonication and direct regeneration (EAR), will be tested to […]

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