Improving GFlowNets for low data drug discovery

GFlowNets are generative networks that consider the generation process as a flow network. They are theoretically better at handling the difficult cases of sampling different modes of a distribution and when different sampling trajectories can yield the same final state. In this work, we hope to explore various improvements to GFlowNets to make them suitable […]

Read More
Morphai

Dream’s continuous landscape of consciousness in science, technology and culture opens up to the gamification of sleep and potential of avatars. Eponymous of the human shapes dream god Morpheus sent to dreamers in Greek mythology, “Morphai” is a trans-consciousness multi-realities game where the animated character’s body movement is controlled by the signals from the sleeping […]

Read More
Leveraging Third-Generation Sequencing to Facilitate Protein Engineering

Hyasynth Biologicals is a synthetic biology company based in Montreal. Hyasynth is focused on developing novel yeast-based production process for plant cannabinoids for the personal care market globally. The MITACS projects at Hyasynth will further the goal of developing and optimizing a yeast-fermentation based production process. The optimization of the enzymes and metabolic pathways in […]

Read More
Quantitative Evaluation and Modeling of Action-Reaction Cycles in Interactive Human Driving Behaviors

This project aims to provide a framework to quantify the interactivity between human drivers in traffic, which could be used to design the decision-making policy for socially-compatible autonomous vehicles. Toward this end, we develop a conditional behavior prediction module based on Gaussian mixture models to jointly capture the dependency of one agent’s reactions on the […]

Read More
Evosep One LC optimization and absolute quantitation of proteins in human and mouse plasma using Multiple Reaction Monitoring and Parallel Reaction Monitoring-Mass Spectrometry

Proteins are sub-cellular molecules that provide important information of how well the body is functioning at a given time. Abnormal increase or decrease in the level of proteins can be indicative of the presence of a disease. Hence, developing tools to accurately measure protein levels in the human body is of utmost importance. Over the […]

Read More
Co-creation of a roadmap for data and information infrastructure for youth homelessness prevention

The research project aims to co-create a roadmap for data and knowledge infrastructure that contributes to youth homeless prevention in Canada. A roadmap will be created through collaboration between researchers, policymakers, service providers, and people with lived experience of youth homelessness. Based on the stakeholders’ concerns, priorities and needs identified in the initial phase, the […]

Read More
Non(Sleep)Social: Reclaiming the silent night

The project focuses on the benefits of wakefulness at night through listening, and listening collectively, in the context of public programs for exhibitions. (NON)SLEEP SOCIAL challenges ideas around sleep and sleep ‘disorders’ such as insomnia as unwanted wakefulness during the night. The project focuses on the potential of all night cultural events within the context […]

Read More
Enhancing sustainability outlook of livestock feed additives production and use: An integrated and model-based approach

Considering the challenge of feeding a growing population, with an increase in the demand for more animal-source foods, efficient use of resources will be essential. Livestock and aquaculture are major contributors to climate change, being responsible for 14.5% of the global greenhouse gas emissions in addition to nutrient losses, leading to water contamination. However, feed […]

Read More
Transformational Specification of Out-of-Thin-Air Memory Models

Much of the performance in today’s computing devices such as mobiles, desktops, supercomputers, etc. can be attributed to concurrency – the ability to perform more than one task simultaneously. In addition, performance of software that run on such devices greatly benefit from the compiler (software that translates our code to be run by hardware) that […]

Read More
Investigating the dose-response of prenatal-THC exposure in adolescent mice

Across the world, rules regarding the legalisation of recreational use of cannabis are changing. This is leading to a perception that cannabis is safe to use: people remain unaware of consequential health risks. The concentration of delta-9-tetrahydrocannabinol (THC), often found in cannabis products, is rising – a concern as THC is known to have psychoactive […]

Read More