Towards personalized surgical spine reconstruction post tumour resection

We aim to develop tools to assess patient outcomes following treatment and removal of bone metastases. We will identify markers for enhanced patient outcomes, so as to predict which patients may benefit from more aggressive treatments to better their quality of life. We also aim to use 3D printed bone implants to help in the […]

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A new flow cytometry platform to evaluate the efficacy of immunotherapies and vaccines

The development of effective immunotherapies, vaccines and immunomodulatory drugs are the main success stories from the last years in drugs development for cancer, infectious diseases and chronic disorders. We are developing a simple and robust new platform to evaluate the next generation of immunotherapeutics treatments at pre-clinical stage. This platform is called Immune Complex Phagocytic […]

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Cisgenic AG704.10 potato cultivar with enhanced late blight resistance and mineral bioavailability

Potato crop suffers from several devastating diseases. Genetic resistance is the best way to manage these diseases but potato is sexually quite incompatible. A novel technology called genome editing offers genetic improvement, similar to conventional breeding, where the susceptible genes in a cultivar are cut and replaced with disease resistance genes from another cultivar, with […]

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Aeration of hydraulic turbines for increased dissolved oxygen

In warm climates warm temperatures cause thermal stratification in hydropower reservoirs inhibiting mixing and leading to deoxygenation of waters at depth (hypolimnium). Turbines withdrawing water at depth result in low dissolved oxygen (DO) in the downstream flow having a large negative impact on the downstream riverine ecosystem. Legislation in the USA and elsewhere now requires […]

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Multiphysics Simulation of Optoelectronic Devices, Circuits and Systems

Traditionally, the microchips that power our communications technology use electrical signals to compute, transfer, and store information. Silicon photonics (SiP) is an emerging field, where structures fabricated on those same microchips replace electrical signals with optical ones, enabling exciting new applications such as optical and wireless communications, bio/environment-sensing, and computing. These new optical microchips are […]

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Refocusing and All-In-Focus Images for Angle-Sensitive Pixel Camera

Currently, the camera in your smartphone can take 2D color pictures. We have developed a new type of camera that can also provide you with depth at each point, not just color. Having depth and where objects are relative to each other in the scene open the door to many different new possibilities, for example […]

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Surgical prehabilitation of cancer patients undergoing surgical resection. Modalities to mitigate the level of anxiety and depression prior to surgery

There is emerging evidence from studies at the Montreal General Hospital supporting the effect of prehabilitation (also referred to as preoperative conditioning) on postoperative outcomes. Increasing physical fitness and optimizing nutrition in cancer patients before surgery can help patients feel physically stronger, return to their community functions sooner and potentially undergo adjuvant cancer treatment earlier […]

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Characterization of graphene-based composites

Blending carbon fillers with thermoplastic materials can lead to a significant improvement of the resulting electrical, mechanical, thermal, and gas barrier properties compared with the unfilled polymer. Graphene, the name given to a material consisting of two-dimension layers of carbon atoms arranged in a hexagonal lattice, has extraordinary properties which make possible to produce a […]

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Developing metabarcoding approaches to describe the fish diversity within a diversity of aquatic habitats

Evaluating the impact of multiple stressors on aquatic ecosystems often requires robust biodiversity estimates. Traditional methods for sampling fish communities are very costly, may have a significant share of inaccuracy and require specialized taxonomic expertise and have numerous other inherent limitations. The general objective of our proposed project is: • to develop and validate genomic […]

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Investigation of electrochemical post-processing procedure for Ti-6Al-4V lattice structure manufactured by Direct Metal Laser Sintering (DMLS)

Additive manufacturing that is commonly called 3D printing has been identified as the 3rd industrial revolution because the outstanding flexibility that it brings to designer in the industry. Because the part is printed layer by layer, almost any complex geometry that can’t be made by conventional methods can be fabricated in a wide range of […]

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Scale-up of a Green Plasticizer

Plasticizers are used to increase the flexibility and workability of relatively rigid polymers such as poly(vinyl chloride) (PVC). For decades, di-2-ethylhexyl phthalate (DEHP and sometimes termed as dioctyl phthalate (DOP)) was the most common plasticizer used in PVC formulations. However, DEHP has been shown to have negative health effects, such as being an endocrine disruptor. […]

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