Docetaxel is a key chemotherapeutic agent for treating locally advanced or metastatic breast cancer, but its effectiveness is often hindered by metabolic inactivation from drug-metabolizing enzymes, leading to multidrug resistance (MDR). This study aims to investigate the anti-metastatic effects of combining kaempferol, a flavonoid known for its anticancer properties, with docetaxel in both 2D and […]

The proposal aligns with an ongoing project conducted by the Gilbrea Dementia SHARE group which investigates the impact of a nature-based support program for older adults with dementia and their caregivers. This study focuses on social health and well-being outcomes for individuals living with dementia. The proposed project aims to identify the socio-ecological factors influencing […]

A poor diet quality and overconsumption of ultra-processed foods represent a looming public health crisis as reflected by a global ‘pandemic’ of obesity and cardiometabolic diseases, including type 2 diabetes. Nutritional studies are prone to bias and misreporting as they typically rely on questionnaires to assess the role of diet on human health outcomes in […]

Design skills are increasingly recognized as a core competency for software professionals. Unfortunately, these skills are difficult to teach because design requires freedom and open-ended thinking, but new designers require a structured process to keep them from being overwhelmed by possibilities. Students need clearly communicated expectations and an easy way of tracking responsibilities to keep […]

Grief supports are necessary to help children process death, without hindering their ability to engage with the world around them from a place of safety, purpose and worthiness. There are unique considerations in providing bereavement services to inner city youth who may be regularly exposed to drug use, while also experiencing higher rates of mortality […]

Polyvinyl Chloride (PVC), a widely used plastic, often includes a variety of additives like plasticizers and stabilizers to meet specific performance needs. However, these complex blends complicate recycling, limiting the ability to produce high-quality recycled PVC (rPVC) that meets current regulatory and environmental standards, and having manufacturers incorporate it into production. To address this, Oligomaster […]

Oligomaster Inc. is developing a Sustainable Product Development Tool that leverages molecular simulation and machine learning to streamline the formulation process for plastic and chemical manufacturers. As industry moves towards sustainable alternatives and faces tighter regulations on certain chemicals, including harmful plasticizers, traditional trial-and-error methods of formulation are no longer efficient or economically viable. This […]

The transition to sustainable energy has heightened the demand for advanced power conversion technologies, crucial for reducing greenhouse gas (GHG) emissions, particularly in Canada, where the transportation sector is a major contributor. Canada aims to achieve 100% zero-emission vehicle sales by 2040, but current projections suggest only 48% of the target will be met, largely […]

20/20 OptimEyes Technologies has developed a nanoparticle technology that can improve treatments for patients. We are moving forward into clinical trials for glaucoma, but we know we can improve other disease treatments with our technology. During this internship, our intern will evaluate other potential therapies where we could use our platform technology and build a […]

Spintronic materials have the potential to improve the density of computer memory and the speed of computer chips. The key feature of spintronic materials is that electronic changes (e.g., electron addition to a molecule) are coupled to changes in magnetic properties. We are particularly interested in transition-metal compounds that undergo redox-induced electron transfer (RIET) because […]

This project aims to tackle a critical challenge in materials science: the efficient extraction of valuable data from a vast array of sources, including scientific literature, patents, and technical reports. By integrating advanced AI language models and tailored prompt engineering, we intend to create an intelligent system that streamlines the process of retrieving polymer-related information. […]

This project aims to experimentally investigate the optimal operating conditions for the reactive crystallization of compounds. A stirred-tank reactor will be set-up and the effects of mixing conditions on the resulting crystal particle size distribution will be investigated. Techniques for the online monitoring the reaction process will be explored, which will be used for model […]