MicroRNAs (miRNA) can be used as biomarkers for different types of cancer diagnostics. Therefore, obtaining point-of-care (POC) device for miRNA detection is of high value. Conventional miRNA sensing strategy usually involves reverse transcription PCR or target recycling strategy and hence those techniques are not suitable for POC devices. In the proposed work, electrochemical sensing strategy […]

The Canadian Association of Midwives (CAM) implements global programs in Africa and the Caribbean, building midwives’ technical skills and strengthening the capacity of midwifery professional associations in our partner countries. CAM seeks two researchers first to assess current best practices in skills and knowledge transfer activities (particularly the transfer of healthcare skills) and civil society […]

Host cell proteins are inevitable contaminants of biopharmaceuticals. Here, we performed detailed analyses of the host cell proteome of moss (Physcomitrella patens) bioreactor supernatants using mass spectrometry and subsequent bioinformatics analysis. Distinguishing between the apparent secretome and intracellular contaminants, a complex extracellular proteolytic network including subtilisin-like proteases, metallo-proteases, and aspartic proteases was identified. Knockout of […]

Deep convolutional neural networks (CNNs) have been tremendously successful in many high-level computer vision tasks, e.g., image recognition and object detection. Although recent works have shown that it is also possible to learn an end-to-end CNN model for low-level vision tasks, e.g., image dehazing, the resulting performance is still not completely satisfactory. For high-level vision […]

Energy-driven pattern formation induced by competing short and long range interaction in multi-species systems is pervasive in the natural world. The phenomenon of self-organization during pattern formation is quite common, and encountered in a variety of fields, such as biological systems like animal coats and skin pigmentation, and physics. As an example, we cite the […]

Voices.com, the largest online marketplace for voice talent, have identified Machine Learning as an enabler for future growth. In particular, incorporating Natural Language Processing (NLP) into structured queries and automatic classification of sample recordings. The first phase of this research involving NLP is in the process of being integrated into production. The second phase will […]

Endocannabinoids are compounds produced by the human body that bind to and activate cannabinoid receptors. There are two major endocannabinoids: anandamide (AEA) and 2-arachidonoylglycerol (2-AG). Both play a role in regulating the firing of brain cells in the nervous system and attenuating immune system responses. As such, the endocannabinoid system is implicated in several clinically […]

In 2000 a novel protein, referred to as GnIH, was discovered to inhibited the release of reproductive regulating hormones in the brain of quail. Since then, GnIH has identified in all studied vertebrate including fish, amphibians, and mammals. It has been shown to decrease hormone synthesis, be produced and act in reproductive tissues, as well […]

Porphyrins and phthalocyanines are important biological molecules that, for example, control respiration of plants (chlorophyll helps convert C02 to oxygen) and heme controls the 02/C02 balance in human blood. Such compounds possess many other regulatory roles. In the presence of light some of these compounds convert oxygen into ‘reactive oxygen species’ (ROS). ROS aggressively attack […]

This research project aims at applying machine learning over the existing financial forecasting methods currently employed in the commercial real estate industry. Businesses are actively collecting more data than what can be analyzed effectively using the standard spreadsheet models which have become industry standard over the past few decades. Machine learning algorithms are known to […]

The proposed research involves both a laboratory component and computational component. Lab research will involve optimization of fork-ligation, optimization of DNA-RNA hybrid ligation, and methods necessary or advantageous in library preparation procedure. The bioinformatics/computational biology research will involve the integration of software packages from the group into the Galaxy Server, expression analysis of small RNA […]

description should also indicate the expected benefit to the partner organization. (Approx 150 words) Since the advent of rail transportation, the integrity of the rail and track conditions play a significant role in ensuring that trains are able to move people safely. As track infrastructure is impacted by ambient temperature and normal wear and tear, […]