Behavioral Analysis of H1 Reconstruction in New Software Environments

The precise prediction of fluid behavior is required in many fields of engineering. Fluid flows are governed by a complex system of continuous partial differential equations (PDEs) which rarely have an exact analytical solution. Computational Fluid Dynamics (CFD) has emerged as a leading method of analyzing fluid flows, by numerically solving the respective PDEs. Current […]

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Hollow Microneedle Manufacturing Process Development

Microneedles are hollow needle structures made out of metal, polymer, or silicon which can be manufactured at any height up to one millimetre, with arrays from one to hundred microneedles, depending on the required playload for delivery. Microneedles platform technology can be applied in medical, cosmetic, biotechnology, and industrial applications. The partner organization has developed […]

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Genomics profiling of peritoneal mesothelioma and patient-derived xenograft models for in vivo biomarker validation

Peritoneal Mesothelioma (PM) is a rare type of cancer affecting the protective membrane surrounding the abdominal cavity and the second most common type of mesothelioma, consisting about 10-20% of the diagnosed cases. The underlying cellular and molecular mechanisms of peritoneal mesothelioma pathology are greatly understudied. In this proposal, we aim to enhance the current knowledge […]

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Determination of ground beef adulterated with beef and pork offal by vibrational spectroscopy

With the increasing numbers of economically motivated food adulteration, sensitive, rapid, portable, and cost-effective detection techniques for food fraud is highly demanded. Ground beef products have the potential to be adulterated by the livestock’s by-products, such as beef and pork offal. Traditional techniques failed to meet the requirements by government, food industry, and consumers (i.e. […]

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Greenest City Conversations Project Part Two

Greenest City Conversations is a research project aimed at developing multiple channels for public engagement on sustainability policies. MetroQuest (MQ) is a digital decision-support tool that generates alternative urban planning scenarios based on user choices, allowing users to evaluate the future consequences of their choices by comparing results and adjusting priorities. The City of Vancouver […]

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Intracellular growth of Mycobacterium tuberculosis: prospects for drug discovery

The success of Mycobacterium tuberculosis (Mtb), the infectious agent of tuberculosis (TB), lies in its ability to primarily infect, reside, and multiply in the lungs of patients. Mtb infects white blood cells termed alveolar macrophages and hides from the host immune response as well as from many antibiotics used for treatment, creating additional challenges for […]

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Assessment of melanotransferrin as an Alzheimer’s disease biomarker

Biomarkers that can reliably detect Alzheimer’s Disease (AD) are essential for disease monitoring and development of drug therapy. We have shown that a protein, melanotransferrin (MTf), is elevated in the blood of humans with AD but is nearly undetectable in age-matched healthy controls. We will further validate MTf as a biomarker in mouse models of […]

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Ultra high performance grease characterization

Greases are highly structured suspensions consisting of a thickener dispersed in lubricating liquid and additives. LB Foster has recently started developing railroad greases that have exceptional product performance. The main objective of this project is to study different grease formulations on a molecular level, using rheological testing and molecular imaging techniques. A fundamental understanding of […]

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Enhancing Software Lifecycle Visibility and Traceability

Teams of specialized workers develop most software. For example, one team may specialize in the requirements that describe what the software is to do. Another team may specialize in producing the software itself. Yet another team may specialize in determining whether the software meets the desired requirements. Supporting communication between all these teams is challenging: […]

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Physiological and environmental factors affecting the migratory behavior and survival of sockeye and steelhead salmon smolts

The great number and variety of factors influencing the survival of migrating salmon smolts in the early marine environment makes it difficult to understand the causes of recent declines in smolt survival and salmon population productivity. We will combine novel methodologies (biotelemetry and biomarkers) simultaneously to examine a variety of factors influencing the migratory behaviour […]

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Unseen Enemy: Global Pandemic Knowledge Mobilization

Our deadliest enemies are the ones we cannot see – viruses or bacteria that lurk and mutate, and grow in resistance, until they become an unstoppable pandemic. This year four interns will work alongside the Tech Samurais company to produce key communication tools that will make effective interventions into the Canadian and global conversation about […]

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