Ovarian cancer is the most lethal gynecologic malignancy and treatment strategies have remained unchanged for decades. A hallmark of tumour progression is the ability to rapidly develop new blood supply; however, aggressive growth signals result in dysfunctional blood vessels that reduce tumour perfusion and promote hypoxia. This tumour microenvironment promotes chemoresistance and suppresses natural and […]

?-Aminobutyric acid (GABA) is a non-protein amino acid that has recently been discovered to play an important role in plant-pathogen interactions. In this proposal, we will comprehensively investigate the potential of GABA metabolism to boost plant immunity against fungal and bacterial pathogens using tomato and Arabidopsis as model plant systems. The effectiveness of exogenous applications […]

The proposed research will use a multiproxy fire history approach to reconstruct wildfire history, severity, and impacts, as well as controls on and changes to the fire regime in the Alberta Foothills region. Fire scar and stand origin records will be used to reconstruct the fire history of the study area over recent decades and […]

There is increasing interest in consuming caffeine through non-traditional methods, e.g., coffee and teas. Previous research has shown that caffeine appears in the bloodstream faster after chewing gum containing caffeine compared to swallowing caffeine pills. This suggests that caffeine can be absorbed faster through the mouth compared to digestion. However, it is unknown how caffeine […]

North American pet food industry utilizes predictive equations such as those including modified Atwater equations to estimate energy density. However research has shown these equations tend to overestimate energy which predisposes companion animals to be in positive energy balance and obese. One method for attaining better predictive energy density models would be to quantify net […]

We appear to be at the beginning of a revolution in the development of new technologies based on quantum science. Over the past several years, Canada has become a world leader in quantum information research and in the development of these emerging quantum technologies. Quantum computers that are based on optical architectures include some of […]

Canine leptospirosis is a climate-sensitive, bacterial, infectious disease of global importance. Despite being vaccine-preventable, leptospirosis is an important cause of morbidity and mortality in dogs. Across North America and the United Kingdom (UK), the prevalence of canine leptospirosis ranges between 4.8-14%, with evidence for increasing prevalence over time. Leptospirosis can be difficult or slow to […]

Ethical data governance practices continue to shift with the emergence of digital technologies like blockchain and artificial intelligence. As these technologies begin to integrate more with climate and nature-based solutions, unique implications appear around data collection, handling, and use. Established concerns about privacy, consent, and data transparency present themselves, along with new considerations where information […]

In the modern era of increased digital and online operations, Security Operation Centers (SOCs) serve as frontline warriors, diligently monitoring and responding to a myriad of cyber security incidents. The SOC team at the project partner’s organization routinely investigates and responds to similar security incidents faced by clients. This project focuses on improving the quality […]

As sustainability is increasingly being questioned from an environmental, social and economic standpoint for food systems, and food insecurity rates are persisting globally, there is a need to improve citizen knowledge about food and food systems to transform them. A primary angle to improve knowledge is through education. Farm to Cafeteria Canada is a key […]

Anthrax is a disease of importance for the human and veterinary fields. It has the potential to be used as a bioweapon; however, this threat is relatively rare compared to the risk it poses for ruminants world-wide. Even though a vaccine is available for cattle it is under-utilized. This project will review the data and […]

Infections, caused by the Candida species have emerged as a significant global health concern. These diseases can range from superficial to life-threatening, affecting various body parts. However, the effective management of Candida infections is increasingly challenged by the growing issue of drug resistance.Focusing on that problem, our research project aims to investigate the antifungal properties […]