Bronchiolitis is one of the most common causes of infant hospitalization and the costs associated with it are large. Since active treatments are mostly ineffective for bronchiolitis, supportive management (including oxygen saturation monitoring) is the main focus of inpatient management. However, ideal oxygen saturation targets for infants hospitalized with bronchiolitis have not been established. This […]

Electrical stimulation of nerves can be used to restore movements to individuals who are paralyzed following spinal cord injury. Our project is divided into two main parts. The first part aims to combine measurements of muscle and nerve activity evoked by electrical stimulation in order to improve our understanding of the mechanisms involved in nerve […]

A consequence of aging is the increased risk of neurodegenerative disease. In the pathogenesis of neurodegenerative diseases is the production of misfolded proteins which can clump together and interfere with normal cellular function. Mitochondria are highly important as they produce energy necessary for cell survival as well as regulate the controlled cell death process of […]

Serial electron diffraction (serial-ED) crystallography is an emerging structural biology method whereby data are collected from protein nanocrystals using a sub-micron-sized electron beam. The method is set to lead the future of nanocrystallography, given its cost-effectiveness and the small amount of sample required. Combining the expertise of the Colletier and Miller teams, the project will […]

Facial plastic surgery is a multibillion dollar industry in North America. Most surgeries are performed for cosmetic reasons, driven by patient goals. 63% of facial plastic surgeons use software to help people visualize possible surgical results. Deep Surface AI is developing a novel visualization software to help surgeons and patients decide on surgical goals. Deep […]

tentree aims to create Science-Based Targets to ensure its climate-positive ambitions. With the rise of corporate sustainability, creating sustainability goals backed by science can push organizations to realize these ambitions. The research will provide foundational work for creating an impact report and sustainability agenda. The aim is to demonstrate tentree’s leadership in the sustainable apparel […]

Neurodegenerative diseases represent one of the largest healthcare burdens in Canada. However, there is limited understanding of how the complex biological factors affect the development of neurodegenerative diseases, thus the era of precision medicine has not to come to treat them yet. Here, we take focus on bioenergetic disruption as a shared risk factor of […]

Continuous miner (CM) optimal performance depends upon various factors which controls the rock-bit (cutter) interaction, including the type and geometry of the bits (cutters), operational parameters (drum speed, advance rate and etc.) and geological setting of the target rock. According to the conducted investigation on CMs performance at Goderich mine, although, these machines have improved […]

The Optical Transport Business Unit of Lumentum Operations LLC is an Ottawa-based R&D operation with interest and experience in the design of Wavelength Selectable Switch (WSS) products for application in optical fiber communications networks. The performance and cost-effectiveness of WSS devices depends on epoxy technologies; epoxy is used to fix free-space optical components in highly […]

The principles of lean engineering design are well documented for the automotive industry – where they have served to revolutionize the efficiencies of North American manufacturing operations. Lean engineering has subsequently been transferred into other sectors – where it continues to generate impressive results. The aerospace industry is faced with demands for efficiency of operations, […]

In theory, hair cells will be reverted back into stem cells and then pushed towards pancreatic progenitor cells to create pancreatic organoids. The goal of the project is to pluck hair follicles from individuals across Canada, cryogenically preserve them and use those follicles towards reprogramming. We want to determine whether or not we can create […]

Plate tectonics is the fundamental process driving geologic deformation and diversity on the planet, as well the engine for the life-sustaining global carbon cycle. The tectonic plates are in continual motion, creating and destroying the massive ocean crustal plates at mid-ocean ridge and subduction boundaries, however, there are still substantial uncertainties with aspects of this […]