In order to investigate proteins in their natural environment one can attach tiny reporter molecules to them that can be traced with appropriate instruments. However, these small reporter molecules may often cause strong perturbations to the functionality of the proteins, or cannot be seen due to experimental restrictions like low concentrations. Bioorthogonal chemistry aims to […]

Medieval nuns were supported by a wide range of people, including lay sisters and brothers who performed much of the physical and manual work of the convent. Yet scholarship has long ignored these members of the monastic community. My research attempts to address this gap by focusing on lay sisters and brothers in fourteenth- and […]

There is massive growth in the area of smart cities (e.g. sensors in streetlights), smart cars, and “smart people” (sensors on people, e.g. wearable computing). In some cities like San Diego, there are cameras and microphones in nearly every streetlight in the downtown core area. Most cars made now have one or more cameras in […]

As of 2012, about three million Canadians suffer from chronic kidney disease. Patients with kidney failure need dialysis or kidney transplantation to survive. LDKT (LDKT) is the best treatment option for many patients with kidney failure, however, it is not used as much as it could be. Patients who belong to ethnic minority groups are […]

Our DNA exists in many different forms. The G-quadruplex is a type of DNA structure made from four strands of DNA. These structures are highly stable and potentially form throughout the genome at clinically important sites. To understand how G-quadruplex structures form, we need to investigate the physical forces that hold the molecules together. When […]

Stroke is a devastating disease that causes a loss of blood to the brain and neuronal death. The sustained inflammation caused by stroke is associated with poor outcomes. Currently, there are no effective treatment options. Exciting new studies have shown a link between bacteria in the gut and brain. This has generated significant interest regarding […]

Free-space optical inter-satellite communication has become an area of key interest in global research and development towards satellite-based communication networks. The aim of this project is to research and develop a thermally stable, multi-watt, optical phased array for the purpose of coherent mechanism-free beam steering in inter-satellite communication systems. Development of this electro-optic chip is […]

Overactive bladder (OAB) is an incurable, chronic medical condition that is characterized by symptoms of urgency, frequency, nocturia and urinary incontinence. It affects approximately 18% of adults and over 30% of the elderly population. Saphenous nerve stimulation is a novel therapy aimed at treating OAB patients. It offers an alternative to bladder medication, which can […]

With the small qubit devices now becoming accessible across various hardware and cloud platforms, it is imperative to find useful tasks for the devices to perform. Such devices are known as NISQ – Noisy Intermediate Scale Quantum – devices. In this regime of a few qubits, we expect the physical qubits to be noisy in […]

Infectious diseases from a variety of pathogens can lead to serious health conditions such as sepsis. To improve the prognosis and decrease the mortality rate of infectious diseases, point-of-care testing (POCT) of blood biomarkers is a critical approach. Testing of biomarkers such as C-reactive protein, IL-6 and procalcitonin could help identify the type of pathogen […]

Organic molecules are used in many areas, for example in drugs or solar cells. However, the development of new organic molecules with desired properties is difficult, time-intensive, and requires a lot of trial and error. A new line of research uses artificial intelligence to partially automate this process and make it more reliable. This project […]

This research project will examine the key factors contributing to the financing success of Canadian rare earth producers from both private and public markets, including Initial Public Offerings on Toronto Stock Exchange and Mergers and Acquisitions transactions. The results from the research will be used to provide an analysis tool for Byron Capital Markets investment […]