Understanding cell-cell interactions with deep learning-based profiling

The aim is to understand how fibroblasts, the most common connective tissue in animals, and cancer cells interact with each other through image analysis. These co-culture imaging screens, containing fibroblasts and cancer cells, will help identify novel signaling mechanism involved in cancer. The objective is to apply deep learning techniques to these image-based assays to […]

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Sleep Disorders among a Population with Traumatic Brain Injury from aWorkplace Safety and Insurance Board (WSIB) Clinic

The proposed research will study the best way to evaluate sleep disorders among persons who suffered a mild to moderate traumatic brain injury (TBI) in the workplace. We will draw upon the Workplace Safety and Insurance Board-insured workers being evaluated at Toronto Rehabilitation Institute, approximately 300-400 annually, for mild to moderate TBI. This study will […]

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Thermal Performance Study of Switch Module Redesign

Thermal analysis is performed on a proposed design change on electronic assembly to ensure that it meets customer requirements (temperature ranges) and is a more cost-effective design. Such design change should be cost efficient. The important aspect, in addition to the design, is interacting with different engineers at different positions in the company. Working with […]

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Value Engineering Feasibility Study for System Controller Chassis/Connector Redesign

Electronic assemblies are used to control various systems in an aircraft. Under normal operating conditions, these undergo vibration, and therefore have an expected life span. Different designs are analyzed to reduce production cost, and these designs must ensure that the electronic components contained within the hardware can tolerate the same operating conditions without failure. With […]

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Realistic Canadian wind power assessment and electricity cost

where the best sites, and combinations of sites are, is critical to facilitate private investment in wind electricity. The proposed research with Brookfield Renewable Energy Partners L.P. will determine the most desirable locations for large-scale wind farm deployment, as well as the cost of electricity supplied by such farms to a selection of Canadian demand […]

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Spatio-temporal patterns of snake bite and suicide in India

In epidemiological studies, most of the existing research tried to investigate the long-term trends (e.g., yearly) in the disease data. However, in this project we will investigate the spatio-temporal patterns of snake bite and suicide in India, both of which are the significant health concerns in India. For both snake bite and suicide, the seasonality […]

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Development of a New Test Method to Evaluate the Impact of Curing on the Near-surface Chloride Penetration Resistance of Concrete

The rate at which chlorides from deicer salts penetrate into concrete towards the reinforcing steel has a strong influence on the time-to-corrosion and service life of concrete structures. Thus, the permeability of the concrete cover layer protecting the reinforcement has to be minimized especially in severe exposure conditions. In addition to the type of concrete, […]

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Interior Construction Progress Monitoring Using Computer Vision and BIM

Progress monitoring is an essential task in all construction projects. A proper progress monitoring can minimize the level of project overruns, which is very common among construction projects but incurring significant loss to public and private funds annually. Manual methods of progress tracking are too infrequent to represent continuous and live insights about the workplace. […]

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Ancestry and health in Latin American native and admixed populations

Using genome-wide data in collaboration with the Peruvian Genome Diversity Project, our goals are: (i)Populations from the Peruvian Central Andes are highly homogeneous. We use Approximate Bayesian Computation and patterns of identity-by-descent to infer when the intensification of the gene pool homogenization on this geographic region started, in the historical context of the Andean prehistory. […]

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Collective Organization and Legal Protection of Precarious and Informal Workers: Lessons from Canada and Brazil

Precarious employment is an increasingly common term used to highlight labour market insecurity (McCann and FUDGE, 2017). In Canada, precarious employment usually relates to atypical forms of work that can present all or some of those characteristics: limited or no social benefits and statutory entitlements, insecurity and low paid, high safety or/and health risks (Vosko, […]

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The morphogenetic effects of DNA damage on the filamentous bacterium Streptomyces

Binary fission, the process in which one bacterium divides into two identical cells, is the most common form of bacterial cell division. However, not all bacteria grow like this. The Streptomyces are a filamentous bacterium that undergo a lifecycle (similar to eukaryotic fungi) which culminates in sporulation. The Streptomyces are a biomedically important bacterium as […]

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New Inhibitors of HIV Infection

A new target on HIV gp120 for interventive drug therapy has been discovered and a company, ViroCarb, initiated to screen for small molecule inhibitors that bind in this site. Two structurally related inhibitors have been isolated from chemical libraries. This internship is to determine the scope of these inhibitors, whether they are able to inhibit […]

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