Title :System-of-Systems Solution with Quantum Simulation for Monitoring, Reporting, Validation, and Verification of GHGs/Carbon Cycle in Biodiversity Ecosystems for SEPLS to Strengthen Sustainable Overview: This project aims to develop a System-of-Systems solution using quantum simulation to monitor, report, validate, and verify greenhouse gases (CO2, CH4, N2O) and the carbon cycle in biodiversity ecosystems, particularly in […]

Artificial Intelligence (AI) is increasingly used in Canada to help make decisions and to deliver public services, but research shows that AI systems can unintentionally reinforce social inequalities, leading to unfair or discriminatory outcomes for minority groups. Biases can appear when AI systems are trained on incomplete or skewed datasets, when development teams lack diverse […]

This community-based research project, undertaken through the U of T Climate Hub Catalyst Internship, partners with the Toronto Chinatown Land Trust (TCLT)-a community-controlled effort to build an inclusive, culturally competent, and ever-evolving Chinatown in Toronto. TCLT acquires, develops, and stewards land in perpetuity for community needs and benefit. Operating with the understanding that Chinatown exists […]

The interns will first conduct market research to determine the demands of the current life sciences industry, including pharmaceutical companies, gene therapy development companies, and companies that offer transgenic animal models. With this data, the interns will work together using a proprietary machine-learning algorithm from Re:Pair Genomics to design a catalog of 5-10 different compact, […]

This project aims to improve a home-based reminder system that supports people living with dementia and their caregivers. The system, called Remindful, uses artificial intelligence (AI) to detect unusual changes in daily routines that may signal health concerns. This research will make the system more trustworthy by adding features that show how confident the AI […]

Peripheral T-cell lymphoma (PTCL) is a type of blood cancer with poor treatment outcomes, as patients often relapse or do not respond to available therapies. A key factor driving the growth of cancerous T cells in PTCL is a protein called ITK, which helps these cells survive by activating biological pathways that boost cell growth […]

Huntington’s Disease (HD) is a debilitating neurodegenerative disease marked by progressive loss of motor control and cognitive function. Presently, there are no disease-modifying therapies. A potential avenue for slowing or stopping HD progression is to target huntingtin (HTT), or polyglutamine-expanded mutant HTT (mHTT), for degradation using proteasome targeting chimera (PROTAC) technology. A PROTAC will bring […]

Cardiac conduction disturbances (CDs) are a prevalent complication of transcatheter aortic valve implantation (TAVI) procedures, which are performed by interventional cardiologists to treat heavily calcified aortic valves. CDs may emerge during or after TAVI, and are typically caused by mechanical injury to the heart’s conduction system, which can be highly challenging to prevent during the […]

Gingival recession affects ~50% of the population and results in the exposure of tooth root surfaces, which leads to an increased risk of dental caries. The gold standard treatment is autologous grafts involving tissue being harvested from the roof of a patient’s mouth, leading to pain and bleeding, the inability to eat, risk of infection, […]

This project aims to improve the early detection of pressure injuries (PIs) in children with disabilities who wear casts for long periods. PIs occur when continuous pressure over bony areas damages the skin, leading to pain, infections, and longer hospital stays. Currently, it is difficult to monitor the skin under a cast because it cannot […]

We propose to develop a microfluidic device that enables the selection of viable sperm directly from semen via a simple dip approach. The device will feature a chamber incorporating a porous membrane. The sperm selection method involves only two steps – users load the device with a semen sample and place the device in buffer. […]

Concussions are a frequently occurring injury with diverse clinical manifestations and an often-challenging recovery. Oculomotor deficits are commonly occurring in persons with concussion, both as an early symptoms and impairment long after the injury. Early assessment and rehabilitation of oculomotor deficits resulting from concussion have the potential to expedite recovery and improve affected individuals’ functioning. […]