Cannabis is the most commonly used drug worldwide. However, there is limited understanding of factors supporting cannabis use (CU) and the development of cannabis use disorder (CUD). There is also a clear association between mood disorders and CUD, but the mechanism underlying this relationship is unclear. There is evidence that major depression is associated with […]

Many governments and other organizations hold confidential data. Theft of that data can be extremely damaging both to the organization and to the people whose data has been stolen. Massive breaches each involving millions of people have been occurring on a regular basis in recent years. New Cyber Security tools are needed to help people […]

As of 2012, about three million Canadians suffer from chronic kidney disease. Patients with kidney failure need dialysis or kidney transplantation to survive. LDKT (LDKT) is the best treatment option for many patients with kidney failure, however, it is not used as much as it could be. Patients who belong to ethnic minority groups are […]

Heat exchangers, used in building heating, ventilation and air conditioning (HVAC) systems to transfer heat from hot to cold fluids, are designed to operate under ideal conditions. However, in practice operating conditions may vary with ambient temperature or humidity. HVAC system efficiency can be improved significantly if fluid flow rates are adjusted in response to […]

type of treatment they will provide to patients. With technological improvements and the availability of a significant volume of data, it is increasingly difficult for care providers to properly evaluate and analyze the options available to them. The current health condition of the patient–reflected in the monitored observations which are recorded in EMR–may depend on […]

Anticoagulation with Warfarin is indicated and required for post-operative cardiovascular patients. However, it is a high-risk medication with a narrow therapeutic range where sub-optimal dosing can lead to complications and even death. While multiple risk factors have been associated to Warfarin sensitivity, the prediction of optimal Warfarin dosing strategies remains ineffective and requires trial and […]

ApoSys is applying the new method to develop an affordable north seeking gyroscopic compass for multiple applications. The cost of such device is too high to be used in many industrial processes. For example the mining industry the device is shared by a few groups of workers to reduce the cost. It has problems for […]

Kelvin Thermal Storage is developing a technology to convert the inexpensive, off-peak/excess or renewable energy into a thermal energy. The technology uses graphite as the heat storage media and carbon composites as heating elements. In order to protect the carbon based components from oxidation by the heat-carrying media (an inert gas containing trace amounts of […]

In recent years, the concern with data reproducibility in preclinical research data has increased significantly. A survey performed by Nature showed more than 70% of published research is not reproducible and the issue is more concerning when it comes to biomedical research with only 10% of published work able to be reproduced. Scientists study the […]

A reduction in the levels of the cellular prion protein (PrPC) is expected to ameliorate cellular toxicity in both Alzheimer’s disease (AD) and prion diseases. The latter are invariably fatal diseases that include Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy (BSE), also known as ‘Mad Cow Disease’, in cattle. To identify a rational method […]

Personalized and precise treatments are the keys to improve prognosis of cancer patients and are also the main strategy of Sunnybrook Hospital. This project aims to stratify patients with colorectal cancer liver metastases (CRM) based on their disease subtype and risk using magnetic resonance imaging, which is routinely used in the diagnosis, staging and operative […]

Spiral tubes and rings have been broadly used in the manufacturing sector, especially for the automobile industry. However, the failure of the rings will significantly shorten the service life of components, even leading to a disaster when the part is under operation. Generally, these tubes and rings are made from steel sheets spirally using the […]