The goal of this research project is to exploit a recent discovery made at Université de Sherbrooke and develop novel antibacterial agents for difficult to treat bacterial infections. The project will target both Gram positive and Gram negative bacteria, using a combination of structural biology, molecular modeling medicinal chemistry and microbiology.

New studies have implicated the gut as the staging area for the start of Parkinson’s disease. Disruptions in the gut biota can promote the formation of toxic protein seeds that can move from the gut into the brain, spreading through the brain and causing progressive loss of neurons and problems with movement. It still needs […]

Improving the design and operation of open pit mines by better understanding and modeling of spatial variation of rock mass properties, can bring economic benefits to the mining industry. The proposed research project aims to develop an innovative large-scale discrete fracture network (DFN) model that is spatially constrained based on the recorded fracture data from […]

Le laboratoire Fesko cultive des microalgues afin de produire des molécules isotopiques pour le marché pharmaceutique. Une problématique de contamination biologique des cultures est apparue dans les dernières années et Fesko recherche des solutions afin de la contrôler et maintenir la productivité des microalgues. Deux méthodes seront étudiées pour identifier l’ensemble des microorganismes indésirables et […]

One challenge to industry adoption of products and services based on Machine Learning and Artificial Intelligence is that their inner workings are often not discernable to human operators. When operators can’t reason about theit tools they tend to make poor decisions about how and when to rely on them. This ultimately limkitsthe effectiveness and efficiency […]

The use of ionic liquids (ILs) in enhanced oil recovery is considered a new and promising technology as it has never been tested in any pilot plant or reservoir field. ILs are very similar to surfactants as they help reduce the interfacial tension, change the wettability of the reservoir, and some have strong viscous effect, […]

Legionnaires is a disease caused by the bacteria Legionella pneumophilia present mostly in aquatic environments. The first outbreak of this disease was recognized in 1976 in Philadelphia and the most recent one in July 2019 in Atlanta. Diagnosis of the disease isn’t early and thus need to be prevented by regular treatment. Treatment of water […]

How do you build trust with an audience expecting a factual, reported story while adding elements of performance to it? This research project explores the potential of the live stage for non-fiction narrative. By experimenting with different models of audience-focused experiences, it aims to answer questions like: How can live journalism rebuild trust between the […]

The Wankel rotary engine has long been seen as a good engine for aeronautical application, but sealing problems is still a challenge that limits its utilisation. Minimizing oil consumption in rotary engine is essential to limit hydrocarbon emissions and minimize overall mass of the engine. Internal oil leaks from the crankcase to the combustion chamber […]

The objective of this project is to develop and customize a cosimulation platform capable of integrating multi-formalism simulators for SG cybersecurity analysis. This enables one to provide a cosimulation platform which is characterized by scalability (no limitation in terms of nodes/buses of communication/power systems), compatibility with the Functional Mock-up Interface (FMI) standard and capability of […]

Developing technology capable of onsite medical diagnostics is crucial for health-care delivery in clinical and emergency settings. To perform on-site diagnostics, health-care practitioners need compact, inexpensive, and user-friendly equipment. Alentic Microscience has developed a system that uses small volumes of blood for cell counting and serum tests, occurring at the site of blood extraction. This […]

A decommissioned mine facility in Canada is looking for a new and innovative way to handle mine waste and reclaim the mine site. The potential solution to this problem is the use of microorganisms which are capable of producing calcite, or cement, as part of their natural biological process. These microorganisms will be combined with […]