Les aptazymes sont des molécules d’ADN ou ARN capables de prendre des conformations très particulières afin d’interagir spécifiquement avec des cibles moléculaires précises, de la même manière qu’un anticorps interagit avec son antigène. Additionnellement à ceci, les aptazymes sont capables, subséquemment à la reconnaissance de leur cible, de réguler l’expression de gènes. Avec ces puissants […]

The oncogenic kinase AKT1 is a prime therapeutic target, but its function cannot be easily researched as AKT activation in cells requires stimulation of cells with an unspecific growth factor that alters all cellular signaling. I designed a new method to deliver an already activated, phosphorylated AKT1 protein to cells that do not require the […]

Les tendances récentes liées au sport et à l’aménagement du territoire interpellent de plus en plus à la résolution d’enjeux sociaux et territoriaux tout à fait conjoints. D’un côté, les manchettes récentes reflètent des desitératums locaux d’instances privées et publiques de tous les azimuts, qui ont à jongler avec un marché de sportif de plus […]

Bien que des médicaments peuvent soulager certains symptômes psychotiques, ils ne sont pas suffisants à eux seuls pour mener au rétablissement des patients. L’identification et le traitement des comorbidités, dont l’addiction aux jeux vidéo (AJV), constituent une avenue prometteuse pour favoriser cette situation. Il n’existe aucune donnée concernant cette dépendance chez les patients souffrant de […]

Inner-city organizations in Winnipeg have long called for transformation of the policies and practices that created injustice for inner-city residents. This year’s State of the Inner City report uses precedent studies to identify funding models that foreground community leadership, and knowledge translation and community development events to celebrate the people and community organizations of the […]

Tensor networks are a quantum inspired technique that provide useful mechanisms for solving hard problems, usually in the realm of quantum mechanics and many-body systems, through the manipulation and operation of tensors. The main challenge underlying this project is the productionalization of a quantum-inspired deep learning algorithm which currently exists as a proof of concept […]

Watersheds in the coastal regions of British Columbia are comprised of rugged mountains and high storm runoff, rendering streams prone to increases in snowmelt during rain-on-snow (ROS) events due to forest harvesting. Importantly, both forest harvesting operations and ROS events are widespread in the transitional snow zones of Vancouver Island, BC. Correspondingly, they routinely experience […]

Dans le contexte communicationnel et technologique actuel, les enfants se retrouvent face à une prolifération d’informations et de contenus. Cette dynamique ouvre grande la porte un phénomène de désinformation poussé, tout particulièrement, par la communication numérique. Or, le numérique est aussi porteur d’opportunités de contre-information et les enfants ont la capacité de se montrer critiques […]

Over the last five years, it has become possible to estimate the capacity of existing, sometimes damaged, utilities and other infrastructure systems to support the local population in war zones. This estimation currently relies on satellite data to provide a basic map of what infrastructure is where. However, it is often difficult o get access […]

This project, sponsored by Safran Landing Systems Canada (SafranLS), involves the development of engineering techniques that enable rapid conceptual design of aircraft landing gear. The goal is to speed the early design of new landing gear to enable SafranLS to produce more, faster bids to manufacture landing gear for new aircraft at their two Canadian […]

Solarvest has developed a cutting-edge technology that enables algae to produce hydrogen in a continuous cycle in a single vessel. The hydrogen is released along with carbon dioxide and water, and intermittently the algae needs to be permitted to carry out photosynthesis, which generates oxygen. This project entails the construction, installation and testing of a […]

Making future projections about quantities of interest is a key component of decision-making, which has broad applications. For instance, in healthcare, one may be interested in monitoring the severity level of a disease given a treatment plan, while carefully accounting for potential sources of uncertainty. Alternatively, one may be interested in predicting the occupancy level […]