Biomarkers for detection of breast cancer and multiple myeloma using liquid biopsy

Blood tests are highly sought after to enable earlier cancer detection. We previously developed a blood test for breast cancer that is in prospective clinical study in Alberta, Manchester (UK), Oklahoma (USA) and South Korea. The proposed project will investigate some clinical samples collected through this work to support the primarily focus of identifying biomarkers […]

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Perioperative Opioid Usage Quality Improvement [CDTS-PDF1]

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

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Developing rAAV-mediated retinal gene therapy to improve vision for ZellwegerSpectrum Disorder – Year Two

Peroxisome Biogenesis Disorders of the Zellweger Spectrum (PBD-ZSD) are a group of inherited genetic disorders caused by mutations in any one of 13 PEX genes. Individuals with the common PEX1-G843D mutation consistently develop a retinopathy that progresses to blindness. To test whether we could slow visual loss in these patients, we performed a proof-of-concept trial […]

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Perioperative Opioid Usage Quality Improvement [CDTS-PDF1] – Year two

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

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Perioperative Opioid Usage Quality Improvement [CDTS-PDF2]

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

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Perioperative Opioid Usage Quality Improvement [CDTS-PDF2] – Year two

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

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Photo-curable Polysiloxane Resins for Engineered Ferroelectret Films

Polymer ferroelectrets are light weight and flexible materials that display piezoelectric behaviour. These properties make them ideal for use as transducers in the aerospace industry. However, the traditional methods used to prepare high performance polymer ferroelectrets cannot be used for large scale manufacturing due to poor reproducibility or high cost. Furthermore, these manufacturing techniques rely […]

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Eng/aging and HIV: Knowledge Exchange Between Administrative Data Project and Aging Individuals with HIV/AIDS in British Columbia

To an unprecedented degree in the history of HIV/AIDS, people with HIV/AIDS (PLHIV) are aging largely owing to the success of treatment. As a relatively new phenomenon, research on HIV/AIDS and aging is only just emerging, and remains largely epidemiological in focus. One leading epidemiological study called COAST comes from the B.C. Centre for Excellence […]

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Eng/aging and HIV: Knowledge Exchange between Older Adults Living with HIV and Big Data Researchers in British Columbia – Year two

To an unprecedented degree in the history of HIV/AIDS, people with HIV/AIDS (PLHIV) are aging largely owing to the success of treatment. As a relatively new phenomenon, research on HIV/AIDS and aging is only just emerging, and remains largely epidemiological in focus. One leading epidemiological study called COAST comes from the B.C. Centre for Excellence […]

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Punching Shear Behavior of Glass Fiber-Reinforced polymer Reinforced Concrete Slab-Column Edge Connections Under Lateral Cyclic Loading

The applicability of reinforcing slab-column edge connections with fiber-reinforced polymer (FRP) bars in resisting gravity loads has been validated through several investigations. The elastic nature of FRP reinforcement raises concerns about the feasibility of using this type of reinforcement in reinforced concrete (RC) structures in seismic regions. To date, only one study has been conducted […]

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