Development and Delivery of Inhibitors for Viral Pathogenic Deubiquitinases

In human viral diseases, misbehaviour of the cellular machinery utilizing ubiquitin is frequently observed. Ubiquitin is a small protein that attaches to target proteins in human cells and signals for their destruction. Human deubiquitinases are enzymes that remove ubiquitin to keep protein levels in balance. Viral pathogens have evolved proteins that mimic human deubiquitinases to […]

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Development and Delivery of Inhibitors for Viral Pathogenic Deubiquitinases – Year Two

In human viral diseases, misbehaviour of the cellular machinery utilizing ubiquitin is frequently observed. Ubiquitin is a small protein that attaches to target proteins in human cells and signals for their destruction. Human deubiquitinases are enzymes that remove ubiquitin to keep protein levels in balance. Viral pathogens have evolved proteins that mimic human deubiquitinases to […]

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Versatile applications of a safe and efficient peptide in gene/drug delivery

Gene therapy is one of the most attractive new therapeutic strategies in the treatment of multiple diseases. However, to apply gene therapy in clinic, an efficient and safe delivery system must be developed to transport these therapeutic reagents to target organs. The existing gene carriers suffer from either high cytotoxicity or immunogenicity problems, which will […]

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Development of Cell-Based Functional Assays to Accelerate Commercialization and Therapeutic Application of Recombinant Antibodies

Antibodies are the fastest growing segment of the pharmaceutical market, and with modern engineering technologies antibodies can be programmed to target devastating diseases. Within the immune system, antibodies fight invading bacteria and viruses. High-quality synthetic antibodies directed to disease-related targets have immense therapeutic potential. Development of cell-based assays to enable rapid identification of functionally active […]

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Chromosome Engineering for Bioproducts from Methanotrophs

Currently Metagenom Bio Inc. offers contract research services in environmental microbial species profiling. Applications for this service include the monitoring of biogas operations, greenhouses, and mining processes. Metagenom Bio wishes to offer solutions that use microbes to generate value-added products. Biogas reactors can break down waste products and produce methane, or natural gas. This methane […]

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Chromosome Engineering for Bioproducts from Methanotrophs – Year Two

Currently Metagenom Bio Inc. offers contract research services in environmental microbial species profiling. Applications for this service include the monitoring of biogas operations, greenhouses, and mining processes. Metagenom Bio wishes to offer solutions that use microbes to generate value-added products. Biogas reactors can break down waste products and produce methane, or natural gas. This methane […]

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Integrated hydrodynamic and water quality modelling tool for the Toronto Waterfront

The goal of this project is to develop the first ever high definition integrated water circulation and water quality model for the Toronto Waterfront. As one of the most urbanized freshwater ecosystems with complex geometries and physical processes, Toronto Waterfront is in an urgent need for modern scientific tools that can support effective environmental management […]

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Design and Development of a High-Resolution Sensory System for Detection of Biogenic Signals

The main focus of this project will be conducting research and developing novel sensory systems to be used in various agricultural environments. The proposed research project also involves development of interpretation algorithms and data-mining software. Ecoation Innovative Solutions (EIS) developed a technology that monitor and interpret different plant signal patterns. The objectives of the proposed […]

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Design and Development of a High-Resolution Sensory System for Detection of Biogenic Signals – Year Two

The main focus of this project will be conducting research and developing novel sensory systems to be used in various agricultural environments. The proposed research project also involves development of interpretation algorithms and data-mining software. Ecoation Innovative Solutions (EIS) developed a technology that monitor and interpret different plant signal patterns. The objectives of the proposed […]

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Evolved Radio Access for Wireless Cellular Communication Systems

The continuously increasing demand for wireless access, driven by the increasing requirements of our connected society, is pushing current wireless cellular communication systems to the limits of their capacity. The objective of this project is to continue the successful collaboration with our industry partner (Telus Corporation) to further contribute to the evolution of current generation […]

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Evolved Radio Access for Wireless Cellular Communication Systems – Year Two

The continuously increasing demand for wireless access, driven by the increasing requirements of our connected society, is pushing current wireless cellular communication systems to the limits of their capacity. The objective of this project is to continue the successful collaboration with our industry partner (Telus Corporation) to further contribute to the evolution of current generation […]

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