Dysfonctions dans la fusion et la fission mitochondriale dans des neurones induits dérivés de fibroblastes de patients atteints de Parkinson idiopathique

La maladie de Parkinson (PD) est un trouble du mouvement associé à l’âge, principalement causé par la mort des cellules dopaminergiques du cerveau. Plus de 90 % des cas de PD sont dit idiopathiques (iPD), c’est-à-dire d’étiologie inconnue. Les causes de la mort des cellules dopaminergiques ne sont pas entièrement comprises. Des éléments indiquent que […]

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Development and commercialization of bio-sensor using cholesteric structure of magnetoplasmonic nanoparticle chain

Recently, bio-sensing R&D using plasmonic has been actively carried out in Korea and overseas. The global bio-sensing market is projected to grow rapidly by an average of 11.6% per year, with a high potential for future development and increased demand in the field. Helical nanostructure using magneto-plasmonic nanoparticles exhibit signals in visible light regions such […]

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Confessional Knowing: A critically queer reading of friendships in the letters and journals of modernist women

This project will make use of unique research knowledge and expertise (Gammel) and specialist archive collections within the Modern Literature and Culture Research Centre at Ryerson University, including life writing materials such as autobiographical accounts, diaries and letters of figures, in particular Gertrude Stein and Florine Stettheimer. It aims to develop a queer/feminist methodology, through […]

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Using low-cost, wearable, sensors to detect driver state: Towards development of new algorithms for real-time detection of driver fatigue

Driver drowsiness is one of the leading causes of road-based crashes. Using a driving simulator study, I plan to help with the collection of data on drowsy drivers, analysing drivers’ physiological metrics, such as eye-tracking, heart rate variability and skin conductance, using low-cost consumer grade sensors. Using sensor fusion of the physiological data, I will […]

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Nickel-Catalyzed ?-Arylation of Secondary Amides

Within the realm of transition metal-catalyzed reactions, considerable interest lies in the ability to generate carbon-carbon linkages using cheap and abundant catalysts and reagents, as products derived from these couplings are widespread amongst bioactive molecules including pharmaceutical and agricultural agents. The importance of catalyst design in facilitating particularly challenging couplings of this type cannot be […]

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Investigation de la localisation cellulaire de l’effecteur 51690 de Melampsora larici-populina.

Melampsora larici-populina est un très petit champignon causant la maladie de la rouille du peuplier. Une fois qu’il s’est incrusté dans une de ces plantations, ce dernier cause d’énormes pertes financières. Pour y arriver, celui-ci injecte des petites protéines afin de déjouer ses défenses immunitaires et de s’approprier ses nutriments pour se développer. Pour arriver […]

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Choosing Coral Winners

The aim of this project is to analyse symbiont and microbial communities of F1 corals from different parental lineages (high/low heat tolerant) during a mild heat stress/natural bleaching event in order to identify communities/traits which are associated with heat tolerance.

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Comparative Data Analysis in Political Aesthetic Strategies: The Persuasive Propaganda of the Italian Populist Right on Facebook and Twitter

This research project informs an essential part of my broader doctoral research which investigates the aesthetic and rhetoric practices developed by today’s far-right populist movements for their propaganda and communication on social media. Working along with Professor Vijay Mago and DaTALab researchers I will generate, collect, and analyse a wide range of new and original […]

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Treeline advances in a changing climate: understanding how climate affects reproduction and early life stages in Black spruce

Northern high-latitude ecosystems experience disproportionate levels of climate change. This strongly affects the previously temperature-limited vegetation in the sub-arctic tundra. Treelines, the boundaries between forests and the tree-less tundra, are expected to shift northwards in response. However, only half of the examined treelines have advanced since 1900. Why warming is associated with treeline advances in […]

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Robust and practical tools for imaging vascular reactivity in the brain

Vascular disease (problems with blood vessels) are a leading cause of death and disability. Stroke alone (blockage of blood vessels) is the 4th biggest killer globally (3rd in Canada), most disabling (2/3rd of survivors disabled) and costs society ~£26 billion a year in the UK. It can be hard to detect. A brain that has […]

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Machine Learning for the Discovery of Metal–Organic Frameworks for Hydrogen Storage Applications

Metal–organic frameworks (MOFs) are a class of crystalline materials with ultrahigh porosity, and high surface areas. With these properties, along with variability for both the organic and inorganic components of their structures, MOFs are of interest for potential applications in clean energy, most significantly as storage media for gases such as hydrogen and methane, and […]

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