Our DNA exists in many different forms. The G-quadruplex is a type of DNA structure made from four strands of DNA. These structures are highly stable and potentially form throughout the genome at clinically important sites. To understand how G-quadruplex structures form, we need to investigate the physical forces that hold the molecules together. When […]

Proteomics have revolutionized bioanalytical chemistry in the past two decades. However, to achieve deep qualitative and quantitative analysis of complex protein samples a significant amount of instrument time (liquid chromatography – mass spectrometry) is required. The major problem stems from the fact that single protein generates many peptides during typical proteomic sample preparation. Limiting this […]

Le processus de cyberne?tisation des socie?te?s a modifie? de manie?re pre?gnante les structures communicationnelles, politiques, e?conomiques, culturelles et sociales, alors que le Web 2.0 a profonde?ment bouleverse? la nature et la porte?e des interactions sociales ainsi que les usages sociaux du cyberespace. Les pratiques d’exposition en ligne comportent toutes un risque et un coût social […]

Renal cell carcinoma (RCC), the most common type of kidney cancer, is characterized by heterogeneous tumor biology and clinical outcomes. Due to the indeterminate behavior of RCC and the absence of routine biomarkers, it is difficult to identify individuals at risk to develop RCC, and patients who are at high-risk of relapse. There are also […]

Les modèles climatiques de surface continentale utilisent une discrétisation spatiale de l’ordre de la centaine de kilomètres et reposent sur l’hypothèse de flux hydrologiques essentiellement verticaux. Ce choix, guidé par des raisons de temps de calcul, conduit à négliger la variabilité hydrologique sous maille et, de ce fait, à proposer des lois et paramètres effectifs […]

Any physical processes that we aim to study in space have probably been influenced at some point by the process of star formation. Whether it be the interstellar gas and dust, the formation of clusters of stars, or galaxy evolution, star formation plays a role as a strong driving force for the physics behind these […]

Acute lymphoblastic leukaemia (ALL) is the most common malignant tumour in childhood. Over the years, the treatment of ALL has improved considerably. Intensive chemotherapy administered during the treatment protocol is nevertheless associated with adverse drug reactions. One of the adverse reactions associated with several anti-leukemic drugs is severe neutropenia, leading to life-threatening infections or frequent […]

Premenopausal women typically have lower blood pressure responses to static exercise compared to age matched men despite similar relative exercise intensity. Some research attributes this difference to an innate effect of biological sex due to differences in metabolism and sympathetic transduction, but work from our lab shows that matching for muscle strength abolishes within and […]

It is well-known that the growth of young firms accounts for a disproportionate share of employment growth and the associated economic welfare. In Canada and Japan, small- and medium-sized enterprises (SMEs) represent around 99.7 percent of each country’s total firms and over 70 percent of each country’s total employment. However, SMEs are known to suffer […]

In this research project, we wish to further understand turbulent flows and the laws that govern them. In particular, we hope to mathematical understand the phenomenon known as “anomalous dissipation” or the “zeroth law of turbulence”. This anomalous dissipation refers to when the viscosity coefficient in a fluid approaches zero, the rate of energy dissipation […]

Depuis 2014, au Brésil, les peuples autochtones élaborent des protocoles de consultation et de consentement pour les projets d’extraction et de développement qui seront réalisés sur leur territoire. Ces protocoles peuvent être fondés sur leurs traditions juridiques et leur interprétation des droits des peuples autochtones reconnues par le droit national et international. Ce projet de […]

A stochastic model was recently developed to theoretically estimate per capita water consumption for various lifestyles, based on specific domestic water use activities. The intention is to populate this model with data from the City of Montréal, bearing in mind that metering of water consumption is uncommon in the study area. Therefore, calibration and verification […]