Development and Validation of Software for the Three-dimensional Quantification and Visualization of Blood Flow Hemodynamics in Patients with Aortic Insufficiency using 4D flow MRI.

The most common cause of chronic aortic insufficiency (AI), a backwards leaking of blood through the aortic valve, are congenital valve disease, degenerative valve disease, and primary diseases of the surrounding aorta. Current management of severe AI is to surgically replace the valve based upon generic 2D imaging measures of severity and progression. However, 4D […]

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Development and Validation of Software for the Three-dimensional Quantification and Visualization of Blood Flow Hemodynamics in Patients with Aortic Insufficiency using 4D flow MRI. Year 2

The aim of this proposal is to assist in the development and validation of a dedicated 4D flow MRI analysis software for the evaluation of aortic valve insufficiency. Before being commercialized this software requires validation considering the large amount of data required to be pre-processed (over 2,000 files per case), elemental data corrections, data analysis […]

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Smart fusion of multi-sensors for UAVs Navigation

Nowadays, there is a rapid increase in the use of Unmanned Aerial Vehicles (UAVs) for commercial and civil applications. Fully autonomous or remotely controlled UAVs requires a reliable and continuous navigation system providing meter level accuracy. The cost, size, and power demand of navigation systems providing this level of accuracy preclude their use on commercial […]

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Smart fusion of multi-sensors for UAVs Navigation – Year 2

The main outcome of this Mitacs-sponsored project will be a robust navigation software capable of providing accurate navigation solutions for commercial Unmanned Aerial Vehicles (UAVs). Such a software will further elevate the industrial competitiveness for the partner corporation, the Profound Positioning Inc. (PPI). After finishing this project, PPI will be able to offer more comprehensive […]

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Fast and robust real-time precise point positioning

Current real-time precise point positioning (PPP) systems still suffer significant challenges. One is its long position convergence time necessary before precise position solutions become obtainable. Another is its sensitivity to the loss/latency of high-frequency precise orbit and clock corrections, resulting in degraded performance. Those challenges have limited PPP’s adoption in many applications. This project aims […]

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Innovating in-field DNA acquisition for enhanced microbiologically influenced corrosion diagnostics

Corrosion of metal-based infrastructure (for example, pipes) is an enormously costly problem faced by many industries including power generation, oil production, transportation, beverage production and water storage and distribution. It is now known that microorganisms can in many cases cause and/or worsen metal corrosion – a phenomenon known as microbiologically influenced corrosion (MIC). OSP Microcheck […]

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Practical portfolio management beyond mean-variance analysis

Portfolio management is crucial to both individual investors and our economy as a whole. For example, pension funds have large amounts of money to invest, taking their risk and gain potential into consideration. The project partner, Alberta Investment Management Corporation (AIMCo), is one of Canada’s largest and most diversified institutional investment fund managers. AIMCo manages […]

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Expression patterns of Wnt/?-catenin signaling pathway components in colon cancer

Extensive research focused on the identification of cellular signaling pathways involved in cancers. A tumor suppressor SOX7 has been implicated in several human cancers: it has been shown to suppress the Wnt/?-catenin signaling that is highly activated in breast cancer and ovarian cancer. This study sets out to determine the role of SOX 7 and […]

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Effects of GDF11 on proliferation and stemness of mesenchymal stem cells

The development of techniques that allow the culture and differentiation of stemcells has opened new research venues and the potential for novel therapies. It has been shown that transplantation of mesenchymal stem cells from bone marrow improved heart function after myocardial infarction. Also mesenchymal stem cells regulate cardiac electrophysiological functions of cardiomyocytes, and protect the […]

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Comparative study of the Canadian and Chinese health care system

The healthcare system of China has been shaped by the co-existence of Traditional Chinese Medicine and evidence based medicine as well as the political reforms of the last century. The ultimate aim of this study is to provide the operational strategies, path selection and scientific evidence for reconstruction the medical insurance system to realize the […]

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