Expression patterns of Wnt/?-catenin signaling pathway components in colon cancer

Extensive research focused on the identification of cellular signaling pathways involved in cancers. A tumor suppressor SOX7 has been implicated in several human cancers: it has been shown to suppress the Wnt/?-catenin signaling that is highly activated in breast cancer and ovarian cancer. This study sets out to determine the role of SOX 7 and […]

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Effects of GDF11 on proliferation and stemness of mesenchymal stem cells

The development of techniques that allow the culture and differentiation of stemcells has opened new research venues and the potential for novel therapies. It has been shown that transplantation of mesenchymal stem cells from bone marrow improved heart function after myocardial infarction. Also mesenchymal stem cells regulate cardiac electrophysiological functions of cardiomyocytes, and protect the […]

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Comparative study of the Canadian and Chinese health care system

The healthcare system of China has been shaped by the co-existence of Traditional Chinese Medicine and evidence based medicine as well as the political reforms of the last century. The ultimate aim of this study is to provide the operational strategies, path selection and scientific evidence for reconstruction the medical insurance system to realize the […]

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Intestinal microbiota transplantation: a potential new therapy for colorectal cancer

Although it is known that the human gut is colonized by a wide variety of microbial populations, many effects of the complex interactions between the human host and microbial symbionts are still not completely understood. The dysbiosis or microbial imbalance of the gastrointestinal tract microbiota is considered to be one of the most important contributing […]

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Design of a gene network implementing an associative memory circuit

The main goal of this research project is to implement an associative memory module in a gene network. The idea is to use the theoretical work already done at the Signals and Systems Laboratory (L2S) and to apply it in the area of genetics. The proposed approach is innovative, as it combines techniques from two […]

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Deterministic Decision Making Using All Geological Realizations

Predicting the quantity of mineral (gold, coper, etc) or hydrocarbon (oil, gas) extracted from a given deposit is difficult. One concern is the uncertainty in the resources underground. A few initial wells or drill holes give us access to an estimate of the quantity of resource, but there is great uncertainty because sampling can be […]

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Estimating reservoir changes in a heavy oil reservoir through application of anelasticity and rock physics analysis to time-lapse seismic data

Oil-sands reservoirs offer huge resource potential with very low decline rates compared to other unconventional exploration targets. Unfortunately, this comes with the trade-off of requiring high initial investment as well as high operating costs. In order for such projects to be economic in the long-term, it is essential that we monitor changes in the reservoir […]

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Emulsion Breaker/Reverse Emulsion Breaker (EB/REB) for Oil Sands Production

Heavy oil production by oil sands surface mining and/or steam assisted gravity drainage (SAGD) processes presents many challenges, but oil and water separation is among the most critical within the industry. The crude oil coming out of reservoir normally carries significant concentration of bitumen and other surface-active species (e.g., asphaltenes, naphthenic acid and even solid […]

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New Adaptive Antenna for RF Heating of Hydrocarbon Reservoirs

Canada owns 13-16% of the world oil supply, but 90% of these reserves are in the form of bitumen, which is as thick as cold peanut butter. This makes bitumen extraction very difficult, if not impossible, without reducing its viscosity. The popular solution is to increase bitumen’s temperature using steam. Sadly, steam strategies can be […]

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Augmented Reality in Surgery

Augmented Reality (AR) is the combination of virtual images with real objects in order to improve perception. It is a rapidly growing field and has many applications in medicine. For this research project we would like to apply AR to the surgical site during a simulated operation in order to provide additional information and improve […]

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