Advanced Data Science Research for Social Good II

Municipal governments and urban centres across Canada are being inundated with data—data that have potential to improve public service. Despite this, local governments do not have enough data expertise to extract insight from these overwhelming datasets. Simultaneously, high-quality personnel (HQP) in the domains of data science and urban analytics lack opportunities to work closely with […]

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The development of monoclonal antibodies for early diagnosis and therapeutic application in Alzheimer’s disease

Alzheimer’s disease is the most common neurodegenerative disorder. The recent immunotherapy brings the hope of treating AD as suggested by several preclinical studies. This project first aims to develop a humanized monoclonal antibody to target the molecules involved in generating a toxic protein of AD, named amyloid ?, and test the application of this antibody […]

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In vitro validation of candidate therapeutic targets for Chronic Obstructive Pulmonary Disease (COPD)

Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder of the lung, which is characterized by shortness of breath and progressive loss in lung function, and one that affects 2.6 million Canadians and 380 million people worldwide. The current therapies are very imprecise and none modifies disease progression or mortality. Therefore, there is a pressing […]

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Computational Statistics with Applications in Genetics/Life Sciences

With the advances in technology and modern computing power, there is a vast increase in data collection and storage in a variety of fields, especially in the fields of medicine and genetics. For example, DNA micro-arrays in genetics now allow scientists to analyze the expression and interaction of millions of genes simultaneously. This massive increase […]

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Chemical and biological characterization of the non-tetrahydrocannabinoid profiles of medicinal plants

We propose to perform detailed studies that characterize chemically and biologically and the unaltered ancestral plant species of the Cannabis genus. Chemically, these studies will provide the chemotype profiles for each parental species for a spectrum of non-tetrahydrocannabinoid compounds. Biologically, these studies will provide the pharmacological profiles for each parental species in conjunction with the […]

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Passages and A/V Performance

Passages and A/V Performances are two sets of art installations that will be prepared for a series of electronic art and music festivals in both the United States and Canada. Passages is the first in a series of installations surrounding Malcolm Levy (of Hybridity Media)’s Other Frames work, developing it in an interactive context.The second […]

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Evaluation of in vivo Hippocampal Volume Assessment in Psychosis Patients at High Field MRI

Schizophrenia is a serious and severe mental disorder of yet unknown etiology. Genetic, developmental and environmental factors have all been implicated in the emergence of the disorder. In particular, abnormalities in both morphology and volume of the hippocampus have been implicated in the underlying mechanisms contributing to the emergence of psychosis in schizophrenia and in […]

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Development of a Raman probe for the on-line determination of pulp properties

Pulp and paper producers would profit enormously from an advanced knowledge of the physical and mechanical properties of a fibre product based upon a measure of the pulp while it is still in process. This project aims to develop such a tool. Using a laser backscattering technique called Raman spectroscopy, will calibrate the molecular bar […]

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Hybrid Microgrid System sizing and energy management based on data analysis and load profile

Research and development efforts in solar, wind, and other renewable energy technologies are required to continue for, improving their performance, establishing techniques for accurately predicting their output and reliably integrating them with other conventional generating sources. The objective of this project is to model a hybrid power system for buildings, which is technically feasible and […]

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Risk Management Perceptions in the Construction Industry of Japan and Canada

Risk can affect quality, productivity, and performance of construction projects. Therefore, risk management is an important part of the decision-making processes in the construction industry. In a typical construction project, many try to transfer risks to other parties, and extensive amount of time is spent on setting the risk allocation terms. This research examines how […]

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Performance based multi-hazard design of high-rise buildings equipped with self-centering systems

Past earthquakes (e.g. 1989 Loma Prieta Earthquake, 1994 Northridge Earthquake, 2010 Haiti Earthquake, 2011 Tohoku Earthquake in Japan) and wind storms (e.g. 2005 Hurricane Katrina, 1992 Hurricane Andrew, 2007 Cyclone Sidr, 2008 Cyclone Nagris) resulted in loss of human lives, economic losses and social disruptions. The current building codes and standards in Canada and the […]

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